Abstract
Vibrio cholerae non-O1 strains are now recognized as causative agents of diarrheal disease(1–9). Some cases of diarrhea due to non-O1 vibrios have been reported to be very similar to cholera, and production of cholera-like enterotoxin by some strains of non-O1 vibrios has been suggested. Zinnaka and Carpenter(10) and Ohashi and his coworkers(11) independently reported that some strains of non-O1 vibrios produced an active substance which was biologically similar to cholera toxin. However, a high degree of purification of the enterotoxin produced by non-O1 vibrios has not been reported. We recently reported(12) that a strain of non-O1 vibrio, serovar 0344, isolatd from fresh water in Louisiana, produces an enterotoxin which is biologically similar to cholera toxin and we demonstrated that the toxin was immunologically identical to cholera toxin in the Ouchterlony immunodiffusion test.
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Yamamoto, K., Takeda, Y., Miwatani, T., Craig, J.P. (1985). Molecular Heterogeneity of Vibrio cholerae Non-O1 Enterotoxins. In: Takeda, Y., Miwatani, T. (eds) Bacterial Diarrheal Diseases. New Perspectives in Clinical Microbiology, vol 9. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4990-4_18
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DOI: https://doi.org/10.1007/978-94-009-4990-4_18
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