Abstract
Bone blood flow is important, not only for the life and growth of bone itself, but also for the homeostasis in the body of several substances and the transport of all the materials that are the subject of this symposium. Its measurement is complicated by multiple arteries and veins and the presence of bone marrow. The main techniques that have been used are: (1) the clearance of “bone-seeking” tracers such as calcium, strontium and fluorine, (2) indicator fractionation using microspheres and (3) the washout of diffusible tracers such as iodoantipyrine or xenon. All rely on radioactive labels and most are invasive, practicable only in experimental animals. Only the first has been attempted in man; its success requires that the extraction from blood by bone of a particular tracer is constant and this assumption has usually been made.
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© 1985 ECSC, EEC, EAEC, Brussels and Luxembourg
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Tothill, P., Hooper, G., McCarthy, I.D., Hughes, S.P.F. (1985). The Variation with Flow-Rate of the Extraction of Bone-Seeking Tracers in Recirculation Experiments. In: Priest, N.D. (eds) Metals in Bone. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4920-1_35
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DOI: https://doi.org/10.1007/978-94-009-4920-1_35
Publisher Name: Springer, Dordrecht
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