Abstract
The functions of bone include mechanical and protective roles and the involvement in mineral metabolism and marrow development. As a connective tissue bone is a special case in that it contains calcium phosphate mineral, is remodelled continuously and it is capable of regeneration without production of scar tissue, [1]. The peculiar constituents of bone tissue, particularly the mineral phase of calcium phosphate, inevitably results in accumulation of many materials introduced into the blood circulation by either natural processes or artificial means. This fact, together with the reasonably long life of newly-synthesized bone in all but the youngest individuals, allows this tissue to act as a sink for a wide variety of substances.
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Triffitt, J.T. (1985). Receptor Molecules, Coprecipitation and Ion Exchange Processes in the Deposition of Metal Ions in Bone. In: Priest, N.D. (eds) Metals in Bone. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4920-1_1
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DOI: https://doi.org/10.1007/978-94-009-4920-1_1
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