Abstract
The topic of this article is the experimental psychology and experimental pharmacology of benzodiazepines as applied to their abuse liability assessment.1 The issues of physiological and psychological dependence on benzodiazepines are considered to be separate topics and will be examined as such.
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References
DeWit H, Johanson CE, Uhlenhuth EH,et al: The effects of two non-pharmacological variables on drug preference in humans. Paper presented at CPDD Meetings, Toronto, June 1982.
Griffiths RR, Bigelow GE, Liebson I: Human drug self-administration: double-blind comparison of pentobarbital, diazepam, chlorpromazine and placebo.J Pharmacol Exp Ther 1979; 210: 301–310.
Griffiths RR, Bigelow GE, Liebson I,et al: Drug preferences in humans: double-blind choice comparison of pentobarbital, diazepam and placebo.J Pharmacol Exp Ther 1980; 215: 649–661.
Griffiths RR, Lukas SE, Bradford LD,et al: Self-injection of barbiturates and benzodiazepines in baboons.Psychopharmacology 1981; 75: 101–109.
Hollister LE: Principles of therapeutic applications of benzodiazepines.J Psychoactive Drugs 1983; 15: 1–2.
Hollister LE, Bennett JL, Kimbell I,et al: Diazepam in newly admitted schizophrenics.Dis Nerv Syst 1963; 24: 746–750.
Johanson CE, Uhlenhuth EH: Drug preference and mood in humans: diazepam.Psychopharmacology 1980; 71: 269–273.
Lukas SE, Griffiths RR: Comparison of triazolam and diazepam in self-administration by the baboon.Pharmacologist 1982; 24: 133.
Martin WR, McNicholas LF, Cherian S: Diazepam and pentobarbital dependence in the rat.Life Sci 1982; 31: 721–737.
Winokur A, Rickels K, Greenblatt DJ,et al: Withdrawal reaction from long-term, low dosage administration of diazepam.Arch Gen Psychiatry 1980; 37: 101–105.
Yanagita T: Dependence-producing effects of anxiolytics, in Hoffmeister F, Stille G (eds):Psychotropic Agents. Part II: Anxiolytics, Gerontopsychopharmacological Agents, and Psychomotor Stimulants. New York, Springer-Verlag, 1981.
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© 1985 MTP Press Limited
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Woods, J.H. (1985). Experimental Abuse Liability Assessment of Benzodiazepines. In: Smith, D.E., Wesson, D.R. (eds) The Benzodiazepines: Current Standards for Medical Practice. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4886-0_15
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DOI: https://doi.org/10.1007/978-94-009-4886-0_15
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8663-9
Online ISBN: 978-94-009-4886-0
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