Abstract
The evidence for two level systems (TLS) in compact proteins such as myoglobin is reviewed, and a model of conformational sub- states based on strongly-interacting TLS is suggested. Thermal and dynamical properties of this model are explored.
Keywords
- Spin Glass
- Characteristic Relaxation Time
- Luminescence Lifetime
- Conformational Substate
- Experimental Time Scale
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
H. Frauenfelder, G.A. Petsko, and D. Tsernoglou, Nature (London) 280, 58 (1979)
F. Parak, E.N. Frolov, R.L. Mössbauer, and V.I. Gol’danskii, J. Mol. Biol. 145, 824 (1981)
R.H. Austin, K.W. Beeson, L. Eisenstein, H. Frauenfelder, and I.C. Gunsalus, Biochemistry 14, 5355 (1975)
R.H. Austin, D.L. Stein, and J. Wong, preprint
H. Frauenfelder, in Structure and Dynamics: Nucleic Acids and Proteins, eds. E. Clementi and R.H. Sarma, ( Adenine Press, N.Y. 1983 ), p. 369
D.L. Stein, Proc. Nat’l Acad. Sci. USA, 82, 3670 (1985)
B. Garish, E. Gratton, and C.J. Hardy, Proc. Nat’l. Acad. Sci. U.S.A. 80, 750 (1983)
P.W. Anderson, B.I. Halperin, and C. Varma, Phil. Mag. 25, 1 ( 1972
W.A. Phillips, J. Low. Temp. Phys. 7, 351 (1972)
S. Hunklinger and W. Arnold, in Physical Acoustics, vol. XII, W.P. Mason and R.N. Thurston, eds. ( Academic Press, N.Y. 1976 ), p. 155
V.I. Gol’danskii, Yu. F. Krupyanskii, and V.N. Flerov, Doklady Akademii Nauk SSSR 272, 978 (1983)
L. Pietronero, preprint.
J.C. Lasjaunias, A. Ravex, M. Vandorpe, and S. Hunklinger, Sol. St. Comm. 17, 1045 (1975)
S. Alexander, C. Laermans, R. Orbach, and H.M. Rosenberg, Phys. Rev. B 28, 4615 (1983)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 D. Reidel Publishing Company
About this paper
Cite this paper
Stein, D.L. (1986). Two-Level Systems in Proteins: Thermodynamic and Dynamic Effects. In: Jortner, J., Pullman, B. (eds) Tunneling. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 19. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4752-8_33
Download citation
DOI: https://doi.org/10.1007/978-94-009-4752-8_33
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8611-0
Online ISBN: 978-94-009-4752-8
eBook Packages: Springer Book Archive