Abstract
The physiological function of insulin in early embryonic life is unknown. Pancreatic insulin synthesis and secretion do not appear in chick embryos until 31/2 to 4 days of development. Nevertheless, immuno-active and bioactive insulin is present in eggs and in chick embryos at day 2 of development. Insulin receptors as well as insulin-like growth factor receptors are widespread in embryo tissues during the first week of embryogenesis. We suggest that endogenous insulin plays a physiological role in early embryo growth and differentiation even before emergence of the endocrine pancreas.
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© 1986 Martinus Nijhoff Publishers, Dordrecht
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de Pablo, F., Bassas, L., Roth, J. (1986). Insulin and insulin receptors in early chick embryo development. In: Augustine, P.C., Danforth, H.D., Bakst, M.R. (eds) Biotechnology for Solving Agricultural Problems. Beltsville Symposia in Agricultural Research, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4396-4_13
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DOI: https://doi.org/10.1007/978-94-009-4396-4_13
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