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Controlled Drug Delivery with Colloidal Polymeric Systems

  • Chapter
Polymeric Biomaterials

Part of the book series: NATO ASI Series ((NSSE,volume 106))

Abstract

A great variety of pharmaceutical preparations are submicroscopic dispersions, such as nanoparticles (1), nanocapsules (2), liposomes (3), macromolecular complexes (4) and the so-called latex formulations (5). Chiefly, because of their submicroscopic particle size, these systems offer a great many interesting applications, not only in the field of medicine but also in agricultural, veterinary and industrial applications. To justify their name, the so called colloidal systems are limited to the size range from a few nanometers up to one micron. In medicine, these types of preparations may be used for parenteral administration, as sustained release injections or for the delivery of an active compound to a specific organ or target site in the body. An ideal colloidal carrier system would transport the drug, entrapped, bound, encapsulated or dissolved in or on the carrier, to its desired site of action and then release the active ingredient at a suitable rate. The system would be non toxic and able to decompose in vivo if injected. At the same time it would have good storage stability.

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Author information

Authors and Affiliations

  1. University of Geneva, School of Pharmacy, Geneva, Switzerland

    R. Gurny

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  1. R. Gurny
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Editor information

Editors and Affiliations

  1. Chemical Engineering Department, Hacettepe University, Ankara, Turkey

    Erhan Piskin

  2. Center for Bioengineering, University of Washington, Seattle, Washington, USA

    Allan S. Hoffman

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© 1986 Martinus Nijhoff Publishers, Dordrecht

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Gurny, R. (1986). Controlled Drug Delivery with Colloidal Polymeric Systems. In: Piskin, E., Hoffman, A.S. (eds) Polymeric Biomaterials. NATO ASI Series, vol 106. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4390-2_12

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  • DOI: https://doi.org/10.1007/978-94-009-4390-2_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8452-9

  • Online ISBN: 978-94-009-4390-2

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