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Immunotoxicology pp 219–233Cite as

MTP-PE, a Synthetic Lipophilic Muramyltripeptide: Biological and Toxcological Properties

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Part of the book series: Developments in Hematology and Immunology ((DIHI,volume 16))

Abstract

Muramyl peptides are biological response modifiers (BRM), and by virtue of this property they exert immune stimulating and immune modulating properties in model systems of antigenic stimulation and also increase prophylactically the resistance to some bacterial and fungal infections (1–4).

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References

  1. Lederer, E. (1980) J. Med. Chem. 23, 819–825.

    Article  PubMed  CAS  Google Scholar 

  2. Dukor, P., L. Tarcsay, G. Baschang (1979) Aim. Reports Med. Chem. 14, 146–167.

    Article  CAS  Google Scholar 

  3. Chedid, L., L. Carelli, F. Audibert (1979) J. Reticulo-endothel. Soc. 26, 631–641.

    CAS  Google Scholar 

  4. Dietrich, F.M., W. Sackmann, O. Zak, P. Dukor 1980 ) In: Current Chemotherapy and Infectious Disease (eds. J.D. Nelson, C. Grassi). Proc. 11th Int. Congr. Chemotherapy 2, 1730–1732.

    Google Scholar 

  5. Fidler, I.J., S. Some, W.E. Fogler. Z.L. Barnes (1981) Proc. Nat. Acad. Sei. USA 78, 1680–1684.

    Article  CAS  Google Scholar 

  6. Fidler, I.J., G. Poste (1981) In: The Prostatic Cell: Structure and Function, Part B. A.R. Liss, New York, 257–267.

    Google Scholar 

  7. Sone, S., E. Tsubura. (1982) J. Immunology 129, 1313–1317.

    CAS  Google Scholar 

  8. Gisler, R.H., G. Schumann, W. Sackmann C. Pericin, L. Tarcsay, F.M. Dietrich (1982) In: Immunomodulation by microbial products and related synthetic compounds (eds. Y. Yamamura, S. Kotani, Excerpta Medica, 167–170.

    Google Scholar 

  9. Fidler, I.J., S. Sone, W.E. Fogler, D. Smith, D.G. Braun, L. Tarcsay, R.H. Gisler, A.J. Schroit (1982) J. Biol. Resp. Med. 1, 43–55.

    CAS  Google Scholar 

  10. Schroit, A.J., I.J. Fidler (1982), Cancer Research, 42, 161–167.

    PubMed  CAS  Google Scholar 

  11. Fidler, I.J., W.E. Fogler, L. Tarcsay, G. Schumann, D.G. Braun, A.J. Schroit (1983) In: Advances in Immuno-pharmacology 2 (eds. J.W. Hadden et al., Pergamon Press) 235–241.

    Google Scholar 

  12. Key, M.E., J.E. Talmadge, W.E. Fogler, C. Bucana, I.J. Fidler (1982) J. Natl. Cancer Inst. 69, 1189–1198.

    CAS  Google Scholar 

  13. Kleinerman, E., K.L. Erickson, A.J. Schroit, W.E. Fogler, I.J. Fidler (1983) Cander Research, 43, 2010–2014.

    CAS  Google Scholar 

  14. Sone, S., S. Mutrsuura, M. Ogowara, E. Tsubura (1984) J. Immunology 132, 2105–2110.

    CAS  Google Scholar 

  15. Dietrich, F.M., B. Lukas, K.H. Schmidtruppin, (1983) Proc. 13th Int. Congress Chemotherapy, Vienna, 91, 50–53.

    Google Scholar 

  16. Koff, W.C. I.J. Fidler, S.D. Showalter, M.K. Chakrabarty, B. Hampar, L.M. Ceccorulli, E.S. Kleinerman (1984) Science 224, 1007–1009.

    Article  PubMed  CAS  Google Scholar 

  17. Kende, M. (1983) Abstract No. 153, 23rd ICAAC, Las Vegas, October 24th–26th.

    Google Scholar 

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Author information

Authors and Affiliations

  1. IBA- Geigy Limited, Basel, Switzerland

    D. G. Braun, P. Dukor, B. Lukas, G. Schumann, L. Tarcsay, M. Court, J. C. Schaffner, T. Skripsky, M. Fischer & P. Graepel

Authors
  1. D. G. Braun
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  2. P. Dukor
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  3. B. Lukas
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  4. G. Schumann
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  5. L. Tarcsay
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  6. M. Court
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  7. J. C. Schaffner
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  8. T. Skripsky
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  9. M. Fischer
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  10. P. Graepel
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Editor information

Editors and Affiliations

  1. Commission of the European Communities, Luxembourg

    A. Berlin (Health and Safety Directorate) (Health and Safety Directorate)

  2. Chemical Industry Institute of Toxicology, Research Triangle Park, North Carolina, USA

    J. Dean

  3. International Programme on Chemical Safety, World Health Organization, Geneva, Switzerland

    M. H. Draper  & E. M. B. Smith  & 

  4. Institute of Pharmacological Research “Mario Negri”, Milan, Italy

    F. Spreafico

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© 1987 ECSC, EEC, EAEC, Brussels-Luxembourg and WHO, Geneva

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Braun, D.G. et al. (1987). MTP-PE, a Synthetic Lipophilic Muramyltripeptide: Biological and Toxcological Properties. In: Berlin, A., Dean, J., Draper, M.H., Smith, E.M.B., Spreafico, F. (eds) Immunotoxicology. Developments in Hematology and Immunology, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4307-0_17

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  • DOI: https://doi.org/10.1007/978-94-009-4307-0_17

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8414-7

  • Online ISBN: 978-94-009-4307-0

  • eBook Packages: Springer Book Archive

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