Abstract
The use of radiolabelled antibodies as radiopharmaceuticals was pioneered by the late Dr. David Pressman in the 1950’s. The radiolabel he used at that time was radioiodine and isotopes of iodine remain attractive as antibody labels because
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a)
Radioiodination is relatively simple.
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b)
A considerable reservoir of experience exists in laboratories of Nuclear Medicine. In the technicalities of radioiodination methods and
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c)
a number of useful radionuclides of iodine exist with widely differing physical properties and the isotope that most closely suits the application under consideration can be chosen (table 1).
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© 1986 Martinus Nijhoff Publishers, Dordrecht
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Mather, S.J. (1986). Radiolabelled Antibodies as Radiopharmaceuticals. In: Cox, P.H., Mather, S.J., Sampson, C.B., Lazarus, C.R. (eds) Progress in Radiopharmacy. Developments in Nuclear Medicine, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4297-4_28
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DOI: https://doi.org/10.1007/978-94-009-4297-4_28
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