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Quantitative Assessment of regional left ventricular function: endocardial landmark motion

  • Chapter
Quantitative Coronary and Left Ventricular Cineangiography

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 51))

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Summary

In this study the hypothesis is tested that the motion patterns of small anatomical landmarks, which can be recognized along the left ventricular endocardial border in contrast angiocardiograms, reflect the motion of the endocardial wall. To validate this hypothesis, minute metal markers were inserted into the endocardium of eight pigs with a novel retrograde transvascular approach. Marker motion was subsequently recorded with roentgen cinematography and compared with the motion of the landmarks along the endocardial contours detected from the contrast ventriculograms with the Contouromat. Linear regression analysis of the directions of the systolic metal marker trajectories and of the endocardial landmark trajectories yielded a correlation coefficient of r = 0.86 and a SEE of 10.3°. Landmark pathways were also measured in 23 normal human left ventriculograms. From this human study it was concluded, that normal left ventricular endocardial wall motion during systole as observed in the 30° RAO view is characterized by a dominant inward transversal motion of the opposite anterior and infero-posterior walls and a descent of the base towards the apex. The apex itself is almost stationary. Based on these observations a widely applicable mathematical model for left ventricular wall motion was developed.

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Authors and Affiliations

  1. Department of Cardiology (Chief: P.G. Hugenholtz, M.D., F.A.C.C.) Thoraxcenter, Erasmus University, and University Hospital Dijkzigt, Rotterdam, The Netherlands

    J. H. C. Reiber Ph.D., P. W. Serruys M.D. & C. J. Slager M.Sc.

Authors
  1. J. H. C. Reiber Ph.D.
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  2. P. W. Serruys M.D.
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  3. C. J. Slager M.Sc.
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© 1986 Martinus Nijhoff Publisher, Dordrecht

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Reiber, J.H.C., Serruys, P.W., Slager, C.J. (1986). Quantitative Assessment of regional left ventricular function: endocardial landmark motion. In: Quantitative Coronary and Left Ventricular Cineangiography. Developments in Cardiovascular Medicine, vol 51. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4239-4_11

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  • DOI: https://doi.org/10.1007/978-94-009-4239-4_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8382-9

  • Online ISBN: 978-94-009-4239-4

  • eBook Packages: Springer Book Archive

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