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Observations on Graves’ Ophthalmopathy; Pathology and Pathogenesis

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Book cover Immunology of Endocrine Diseases

Part of the book series: Immunology and Medicine ((IMME,volume 3))

Abstract

Recognition of a link between the thyroid and the eye as is seen in Graves’ ophthalmopathy (GO) has been attributed to Parry, Graves and von Basedow but observations relating exophthalmos to goitre can be found as early as the 12th century. Despite the growth of a vast literature, considerable uncertainty exists regarding many aspects of this potentially distressing and disfiguring clinical condition, particularly with regard to its pathogenesis and hence to the management of patients with the problem. Many excellent reviews providing an historical perspective and emphasizing the clinical aspects of GO have appeared in recent years1–3. This chapter will therefore focus particularly on information relating to the pathogenesis of GO.

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Authors
  1. R. M. Pope
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  2. M. E. Ludgate
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  3. A. M. McGregor
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Editor information

Editors and Affiliations

  1. Department of Medicine, University of Wales College of Medicine, Health Park, Cardiff, Wales, CF4 4XN, UK

    Alan M. McGregor (Senior Lecturer and Honorary Consultant Physician) (Senior Lecturer and Honorary Consultant Physician)

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© 1986 MTP Press Limited

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Pope, R.M., Ludgate, M.E., McGregor, A.M. (1986). Observations on Graves’ Ophthalmopathy; Pathology and Pathogenesis. In: McGregor, A.M. (eds) Immunology of Endocrine Diseases. Immunology and Medicine, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4171-7_9

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  • DOI: https://doi.org/10.1007/978-94-009-4171-7_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8352-2

  • Online ISBN: 978-94-009-4171-7

  • eBook Packages: Springer Book Archive

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