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Immunological defence mechanisms as a target for antibiotics

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Comparative Veterinary Pharmacology, Toxicology and Theraphy

Abstract

When the immunological defence mechanisms fail to prevent the establishment of infections within the host, the consequence is disease. Particularly under these circumstances, antibiotics have proved to be of remarkable value for therapeutic treatment of bacterial infections. The antibiotic generally interferes with the metabolism of the pathogen, allowing the immune system to eliminate it. In this way, the antibiotic cooperates with the immune system. However, the effect of antibiotics on immunological processes is rarely taken into consideration.

In this paper, we selectively review antimicrobial agents used in veterinary and human medicine with regard to their effects on non-specific and specific defense mechanisms.

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Authors
  1. J. L. Grondel
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  2. W. B. Van Muiswinkel
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Editor information

Editors and Affiliations

  1. Institute of Veterinary Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine, University of Utrecht, P. O. Box 80. 176, 3508 TD, Utrecht, The Netherlands

    A. S. J. P. A. M. Van Miert

  2. J. F. and C. Heymans Institute of Pharmacology, University of Ghent, Medical School, De Pintelaan 185, B-9000, Ghent, Belgium

    M. G. Bogaert

  3. Department of Veterinary Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Ghent, Casinoplein 24, B-9000, Ghent, Belgium

    M. Debackere

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© 1986 MTP Press Limited

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Grondel, J.L., Van Muiswinkel, W.B. (1986). Immunological defence mechanisms as a target for antibiotics. In: Van Miert, A.S.J.P.A.M., Bogaert, M.G., Debackere, M. (eds) Comparative Veterinary Pharmacology, Toxicology and Theraphy. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4153-3_25

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  • DOI: https://doi.org/10.1007/978-94-009-4153-3_25

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8343-0

  • Online ISBN: 978-94-009-4153-3

  • eBook Packages: Springer Book Archive

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