Abstract
Active demyelinating lesions of multiple sclerosis (MS) is charactrized by increased cellularity,presence of numerous macrophages and astrocytes,increased vascularity,and perivenous mononuclear cell infiltrates (Adams,1977).The mononuclear cell infiltrates consist mainly of T lymphocytes (Nyland et al.,1982;Traugott et al.,1983),and a small number of B lymphocytes/plasma cells (Esiri,1980).The macrophages in MS lesions possess receptors for the Fc part of IgG,FcR (Nyland et al.,1980),and show capping of surface IgG indicating that they may be engaged in immune mediated phagocytosis of myelin (Prineas & Graham,1981).
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© 1986 ECSC, EEC, EAEC, Brussels and Luxembourg
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Nyland, H., Mörk, S., Matre, R., Naess, A. (1986). Characterization of T-cell Subsets and Macrophages in Active Demyelinating Multiple Sclerosis Lesions. In: Hommes, O.R. (eds) Multiple Sclerosis Research in Europe. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4143-4_18
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DOI: https://doi.org/10.1007/978-94-009-4143-4_18
Publisher Name: Springer, Dordrecht
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