Abstract
It has, since Charcot’s time, been almost unanimously recognized that the course of MS may take the form of bouts, or it may be chronically progressive, either from the onset or after a number of bouts. The essential histological and immunological difference, if any, between bouts and progress is still a matter of debate. Apart from this genuine problem, different interpretations of terms create new problems. The parameters discussed below have been amply tested in the Goteborg incidence material (Andersen 1980)
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© 1986 ECSC, EEC, EAEC, Brussels and Luxembourg
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Andersen, O., Andersson, M., Broman, T., Zeeberg, I. (1986). Compact Manual for Multiple Sclerosis Registration in Clinical Research. In: Hommes, O.R. (eds) Multiple Sclerosis Research in Europe. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4143-4_12
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DOI: https://doi.org/10.1007/978-94-009-4143-4_12
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