Skip to main content

Compact Manual for Multiple Sclerosis Registration in Clinical Research

  • Chapter

Abstract

It has, since Charcot’s time, been almost unanimously recognized that the course of MS may take the form of bouts, or it may be chronically progressive, either from the onset or after a number of bouts. The essential histological and immunological difference, if any, between bouts and progress is still a matter of debate. Apart from this genuine problem, different interpretations of terms create new problems. The parameters discussed below have been amply tested in the Goteborg incidence material (Andersen 1980)

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Andersen, O., 1980. Restricted dissemination of clinically defined attacks in an MS incidence material. Acta Neurol. Scand., 62, Suppl. 77.

    Google Scholar 

  • Bauer, H.S., 1980. IMAB-Enquöte Concerning the Diagnostic Criteria for MS. In: Bauer, Poser, Ritter: Progress in Multiple Sclerosis Research. Springer Berlin, pp. 555–563.

    Google Scholar 

  • Ebers, G.C., Finuela F.V., Feasby, T., Bass, B., 1984. Multifocal CT enhancement in MS. Neurology, 34: pp. 341–346.

    PubMed  CAS  Google Scholar 

  • Frydán, A., Link, H., Norrby, E., 1978. Cerebrospinal Fluid and Serum Immunoglobulins and Antibody Titers in Mumps Meningitis and Aseptic Meningitis of Other Etiology. Infection and Imnunity, 21: pp. 852–861.

    Google Scholar 

  • Hershey, L.A., Trotter, J.L., 1980. The Use and Abuse of the Cerebrospinal Fluid IgG Profile in the Adult: A Practical Evaluation. Ann. Neurol., 8: pp. 426–434.

    Article  PubMed  CAS  Google Scholar 

  • Link, H., Müller, R., 1971. Immanoglobulins in Multiple Sclerosis and infections of the nervous system. Arch. Neurol., 25: pp. 326–343.

    PubMed  CAS  Google Scholar 

  • Lcwhagen, G., Andersson, M., Blomstrand, C., Roupe, G., 1983. Central Nervous System Involvement in Early Syphilis. Acta Derm. Venereol., 63: pp. 409–417.

    Google Scholar 

  • Olsson, J., Pettersson, B., 1976. Comparison between agar gel electrophoresis and CSF serum quotients of IgG and albumin in neurological diseases. Acta Neurol. Scand., 53: pp. 308–322.

    Article  PubMed  CAS  Google Scholar 

  • Ormerod, I.E.C., du Boulay, E.P.G.H., Callanan, M.M., Johnson, G., Logsdail S.J., Moseley, I.S., Rudge, P., Roberts, R.C., McDonald, W.I., Halliday A.M., Kendall, B.E., Macmanus, D.G., Ron, M.A., Zilka, K.J., 1984. NMR in multiple sclerosis and cerebral vascular disease. Lancet, II: pp. 1334–1335.

    Article  Google Scholar 

  • Poser, C.M., Paty, D.W., Scheinberg, L., McDonald, W.I., Davis, F.A., Ebers, G.C., Johnson, K.P., Sibley, W.A., Silberberg, D.H., Tourtellotte, W.W., 1983. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols. Ann. Neurol., 13: pp. 227–231.

    Article  PubMed  CAS  Google Scholar 

  • Prineas, J.W., 1970. Etiology of multiple sclerosis. In: Handbook of Clinical Neurology. North-Holland, Amsterdam, vol. 9, pp. 107–160.

    Google Scholar 

  • Roström, B.: 1981. Specificity of Antibodies in Oligoclonal Bands in Patients with Multiple Sclerosis and Cerebrovascular Disease. Thesis. Linköping University. Schumacher, G.A., Beebe, B., Kibler, R., Kurland, L.T., Kurtzke, J.F., McDowell, F., Nagler, B., Sibley, W.A., Tourtellotte, W.W., Willmann, T.L., 1965. Problems of experimental trials of therapy in multiple sclerosis: Report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. Ann. N.Y. Acad. Sei., 122: pp. 552–568.

    Google Scholar 

  • Schumacher, G.A., Nagler, B., Sibley, W.A., Tourtellotte, W.W., Willmann, T.L., 1965. Problems of experimental trials of theraphy in multiple sclerosis. In: Hallpike, Adams, Tourtellotte: Multiple sclerosis. Pathology, diagnosis and management. Chapman and Hall, London, pp. 177–201.

    Google Scholar 

  • Sedgwick, E.M., 1983. Pathophysiology and Evoked Potentials in Multiple Sclerosis. In: Hallpike, Adams, Tburtellotte: Multiple sclerosis. Pathology, diagnosis and management. Chapman and Hall, London, pp. 177–201.

    Google Scholar 

  • Vandvik, B., Norrby, E., Steen-Johnsen, J., Stensvold, K., 1978. Mumps Meningitis: Prolonged Pleocytosis and Occurrence of Mumps Virus-specific Oligoclonal IgG in the Cerebrospinal Fluid. Eur. Neurol., 17: pp. 13–22.

    Article  PubMed  CAS  Google Scholar 

  • Vinuela, F.V., Fox, A.J., Debrun, G.M., Feasby, T.E., Ebers, G.C., 1982. New perspectives in computed tomography of multiple sclerosis. AJR, 139: pp. 123–127.

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 ECSC, EEC, EAEC, Brussels and Luxembourg

About this chapter

Cite this chapter

Andersen, O., Andersson, M., Broman, T., Zeeberg, I. (1986). Compact Manual for Multiple Sclerosis Registration in Clinical Research. In: Hommes, O.R. (eds) Multiple Sclerosis Research in Europe. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4143-4_12

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-4143-4_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8338-6

  • Online ISBN: 978-94-009-4143-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics