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Cosmetics, Toiletries and Household Products

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The Future of Predictive Safety Evaluation
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Abstract

The diverse range of raw materials used in manufacturing cosmetics, toiletries and household products is encountered by vast numbers of people over the years, irrespective of age, sex or state of health. Exposure is often prolonged and repeated frequently, in some instances throughout a major part of the lifespan, mostly without medical or other expert supervision. Such a pattern of exposure in all the more advanced countries of the world seldom, in practice, gives rise to overt safety problems of any consequence or to insidious and possibly more serious adverse effects, according to the available evidence. Predictive safety evaluation based on experimental investigation is relatively new to the scene; the earlier way of selecting ingredients by a process of trial-and-error evidently functioned remarkably well on the whole. Inevitably mistakes were made now and again. For example, distinctly hazardous substances such as arsenic, mercury and atropine found their way into cosmetics at certain times but ingredients mostly seem to have been chosen at least partly for their inherent blandness, thereby providing quite an effective safeguard.

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References

  1. Doll, R (1977). Strategy for detection of cancer hazards to man. Nature, 265, 589

    Article  PubMed  CAS  Google Scholar 

  2. Official Journal of European Community (1976). L. 262/169 (76/768/EEC) Council Directive of 27 July 1976 on the Approximation of the Laws of the Member States Relating to Cosmetic Products

    Google Scholar 

  3. Dale, JR and Appelbe, GE (1983). Pharmacy Law and Ethics, 3rd edn, p. 175. ( London: Pharmaceutical Press )

    Google Scholar 

  4. Official Journal of European Community (1979). L. 259/10 (79/831/EEC) Council Directive of 18 September 1979 Amending for the Sixth Time, Directive 67/548/EEC on the Approximation of the Laws, Regulations and Administrative Provisions Relating to the Classification, Packaging and Labelling of Dangerous Substances

    Google Scholar 

  5. HMSO (1984). Cmnd. 9311 Statistics of Experiments on Living Animals

    Google Scholar 

  6. Polak, L (1980). Current concept of allergic skin reactions. Int J Cosmet Sci, 2, 251

    Article  PubMed  CAS  Google Scholar 

  7. Scaife, M (1982). An investigation of detergent action on cells in vitro and possible correlation with in vivo data. Int J Cosmet Sci, 4, 179

    Article  PubMed  CAS  Google Scholar 

  8. Cronin, E (1984). Photosensitivity to musk ambrette. Contact Dermatol, 11, 88

    Article  CAS  Google Scholar 

  9. Dubin, NH, Wolff, MC, Thomas, CL and Di Blasi, MC (1985). Prostaglandin production by rat vaginal tissue, in vitro, in response to ethanol, a mild mucosal irritant. Toxicol Appi Pharmacol, 78, 458

    Article  CAS  Google Scholar 

  10. Davies, R, Skidmore, JW, Griffiths, DM and Moncrieff, CB (1983). Cytotoxicity of talc for macrophages in vitro. Fd Chem Toxicol, 21, 210

    Article  Google Scholar 

  11. HMSO (1984). Cmnd. 9302, The Safety of Goods

    Google Scholar 

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© 1986 MTP Press Limited

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Van Abbé, N. (1986). Cosmetics, Toiletries and Household Products. In: Worden, A.N., Parke, D.V., Marks, J. (eds) The Future of Predictive Safety Evaluation. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4139-7_11

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  • DOI: https://doi.org/10.1007/978-94-009-4139-7_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8336-2

  • Online ISBN: 978-94-009-4139-7

  • eBook Packages: Springer Book Archive

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