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Gas Chromatography (GC)

  • A. Braithwaite
  • F. J. Smith
Chapter
  • 137 Downloads

Abstract

It was nearly 50 years from Tswett’s description of chromatographic separations (1906) to the development of gas-liquid chromatography by Martin and James (1952). Since that time gas chromatography has developed rapidly, particularly during the 1960s, producing sweeping changes in analytical chemistry and in many areas of research and development. It was now possible to separate, quantify, and subsequently identify, components in a mixture, from permanent gases, and hydrogen isotopes to fatty acids and waxes. Although direct analysis is limited to compounds with a molecular weight up to 400–500, derivatives of involatile materials can readily be made which have some measure of volatility without thermal degradation. Preparative-scale gas chromatography offers a method of obtaining very pure compounds and is used commercially in the manufacture of laboratory reagents, drugs and flavours. It is also possible to obtain physicochemical measurements using GC, such as surface properties, kinetics and thermodynamics of separation and adsorption processes which have application in, for example, the development of catalysts.

Keywords

Chromatographic Method Flame Photometric Detector Petrol Vapour Open Tubular Column Nitrogen Phosphorus Detector 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© A. Braithwaite and F. J. Smith 1985

Authors and Affiliations

  • A. Braithwaite
    • 1
  • F. J. Smith
    • 1
  1. 1.Department of Physical SciencesTrent PolytechnicNottinghamUK

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