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Ecological Effects of In Situ Sediment Contaminants pp 67–74Cite as

Sediment-associated contaminants and liver diseases in bottom-dwelling fish

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Part of the book series: Developments in Hydrobiology ((DIHY,volume 39))

Abstract

High concentrations of chemicals have been found in sediments from urban areas of Puget Sound. Hundreds of organic chemicals (including certain aromatic hydrocarbons [AHs] and various chlorinated compounds) were identified. Statistical methods were used to evaluate possible relationships between the chemistry data and fish diseases. Positive correlations were found between the frequencies of liver neoplasms (e. g., hepatocellular carcinoma) and other liver lesions in English sole (Parophrys vetulus) and concentrations of AHs in sediment; such correlations were not found with chlorinated hydrocarbons. Strong evidence was also obtained to show that many organic chemicals in sediment are bioavailable to bottom-dwelling fish. Stomach contents (consisting mainly of benthic invertebrates) from English sole had concentrations of a number of AHs similar to those in the sediment from which the fish were taken. In these same fish, metabolites of many aromatic compounds were found in bile using a procedure combining HPLC with fluorescence detection. Further, the concentrations of certain xenobiotic metabolites in bile were correlated positively with the occurrence of liver neoplasms in English sole.

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Author notes

  1. Donald C. Malins

    Present address: Pacific Northwest Research Foundation, Seattle, WA, 98104, USA

Authors and Affiliations

  1. Northwest and Alaska Fisheries Center, Environmental Conservation Division, National Marine Fisheries Service, 2725 Montlake Boulevard East Seattle, WA, 98112, USA

    Donald C. Malins, Bruce B. McCain, Donald W. Brown, Usha Varanasi, Margaret M. Krahn, Mark S. Myers & Sin-Lam Chan

Authors
  1. Donald C. Malins
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  2. Bruce B. McCain
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  3. Donald W. Brown
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  4. Usha Varanasi
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  5. Margaret M. Krahn
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  6. Mark S. Myers
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  7. Sin-Lam Chan
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Editor information

Editors and Affiliations

  1. International Joint Commission, Great Lakes Regional Office, 100 Ouellette Avenue, 8th Floor, Windsor, Ontario, Canada, N9A 6T3

    Richard L. Thomas  & Trefor B. Reynoldson  & 

  2. International Joint Commission, 8th Floor, 100 Metcalfe Street, Ottawa, Ontario, Canada, K1P 5M1

    A. L. Hamilton

  3. Great Lakes Fisheries Research Branch, Canada Centre for Inland Waters, 867 Lakeshore Road, P.O. Box 5050, Burlington, Ontario, Canada, L7R 4A6

    M. Munawar

  4. Federal Environmental Assessment Review Office, Fontaine Building, 13th Floor, Hull, Quebec, Canada, K1A 0H3

    M. Husain Sadar

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© 1987 Dr W. Junk Publishers, Dordrecht

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Malins, D.C. et al. (1987). Sediment-associated contaminants and liver diseases in bottom-dwelling fish. In: Thomas, R.L., Evans, R., Hamilton, A.L., Munawar, M., Reynoldson, T.B., Sadar, M.H. (eds) Ecological Effects of In Situ Sediment Contaminants. Developments in Hydrobiology, vol 39. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4053-6_7

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  • DOI: https://doi.org/10.1007/978-94-009-4053-6_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8299-0

  • Online ISBN: 978-94-009-4053-6

  • eBook Packages: Springer Book Archive

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