Abstract
In order to achieve a therapeutic effect a radiophamaceutical must be delivered to, and concentrate in, the target organ or lesion for a few days or weeks. The time and concentration should be sufficient to diliver a radiation absorbed dose which will produce the desired therapeutic effect. The radiation absorbed dose will depend on the type of radiation emitted by the radionuclide. Radiations which produce few ionisations per unit path length, eg, x- and gamma rays are not suitable for this type of theraphy, whereas radiations which are locally absored, eg, alpha, beta, internal conversion and Auger electrons, can produce the necessary irradiation. Beta-emmiting radionuclides are usually used in therapy.
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© 1987 Martinus Nijhoff Publishers, Dordrecht
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Lazarus, C.R. (1987). Good Radiopharmacy Practice. Daily Practice with Special Reference to Theraphy. In: Kristensen, K., Nørbygaard, E. (eds) Safety and Efficacy of Radiopharmaceuticals 1987. Developments in Nuclear Medicine, vol 14. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3375-0_17
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DOI: https://doi.org/10.1007/978-94-009-3375-0_17
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