Abstract
Total lymphoid irradiation (TLI), a radiotherapy regimen which has been successfully used for several decades in the treatment of Hodgkin’s disease, was recently shown to result in a long lasting state of immunosuppression (1). In animal experiments, TLI enabled the induction of transplantation tolerance when allogeneic solid organs were transplanted together with bone marrow from the same donor (1). These experimental results prompted several clinical transplantation teams, including our own (2,3), to use TLI for clinical organ transplantation. Preliminary results of these trials are promising.
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© 1987 Martinus Nijhoff Publishers, Dordrecht
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Waer, M., Van Der Schueren, E., Vandeputte, M. (1987). Induction of Transplantation Tolerance After Total Lymphoid Irradiation : Influence of Thymus Transplantation or Blood Transfusions. In: De Clercq, E. (eds) Frontiers in Microbiology. New Perspectives in Clinical Microbiology, vol 13. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3353-8_35
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DOI: https://doi.org/10.1007/978-94-009-3353-8_35
Publisher Name: Springer, Dordrecht
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