Immunocytochemistry and the Pathological Diagnosis of Cerebral Tumours
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Definition of the cell of origin ofa tumour but taking into the account the loss or gain of marker proteins by tumour cells.
Identification of normal and reactive nervous tissue cells and their relationships to tumour cells. Immunocytochemistry has supplemented or even replaced the use of capricious silver stains and dye techniques for light microscopy and has reduced the need for electron microscopy in tumour diagnosis.
Detection of inflammatory cells and lymphocyte subsets within tumours and the use of similar techniques for the diagnosis and classification of lymphomas.
Key wordsImmunocytochemistry Brain-tumours Diagnosis
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- 1.Zulch (K.J.) (ed.): Histological typing of tumours of the central nervous system (WHO, 1979).Google Scholar
- 4.Sternberger (L.A.): Immunocytochemistry, 2nd Edition (Wiley, 1979).Google Scholar
- 5.Weller (R.O.), Steart (P.V.), Moore (I.E.): Carbonic Anhydrase C as a marker antigen in the diagnosis of choroid plexus papillomas and other tumours: an immunoperoxidase study. In: Biology of Brain Tumour. Eds Walker MD and Thomas DGT (Martinus Nijhoff and Dr W Junk 1986), p. 115–120.CrossRefGoogle Scholar
- 7.Weller (R.O.): Color atlas of Neuropathology (Harvey Miller and Oxford University Press, 1984).Google Scholar