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Assay of Anticancer Drugs in Tissue Culture: The Effect of Cell Kinetics and the Mode of Action of Drugs on the Chemosensitivity of Cultures Derived from Malignant Brain Tumours

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Brain Oncology Biology, diagnosis and therapy

Part of the book series: Developments in Oncology ((DION,volume 52))

Abstract

It is a common clinical observation that tumours of similar histology do not always respond identically to the same cytotoxic drugs. Although factors such as drug delivery and host-tumour interactions must play a role in this, other factors, in particular intrinsic drug sensitivity must also be important.

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References

  1. Thomas (D.G.T.), Darling (J.L.), Freshney (R.I.), Morgan (D.): In vitro chemosensitivity assay of human glioma by scintillation autofluorography. In: Paoletti P., Walker M.D., Butti G.H. and Knerich R. eds, Multidisciplinary Aspects of Brain Tumor Therapy. Amsterdam, Elsevier, 19–35, (1983).

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  2. Morgan (D.), Freshney (R.I.), Darling (J.L.), Thomas (D.G.T.), Celik (F.): Assay of anticancer drugs in tissue culture: Cell cultures of biopsies from human astrocytoma. Br. J. Cancer 47: 205–214 (1983).

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© 1987 Martinus Nijhoff Publishers, Dordrecht

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Darling, J.L., Thomas, D.G.T. (1987). Assay of Anticancer Drugs in Tissue Culture: The Effect of Cell Kinetics and the Mode of Action of Drugs on the Chemosensitivity of Cultures Derived from Malignant Brain Tumours. In: Chatel, M., Darcel, F., Pecker, J. (eds) Brain Oncology Biology, diagnosis and therapy. Developments in Oncology, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3347-7_66

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  • DOI: https://doi.org/10.1007/978-94-009-3347-7_66

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8003-3

  • Online ISBN: 978-94-009-3347-7

  • eBook Packages: Springer Book Archive

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