Abstract
It is a common clinical observation that tumours of similar histology do not always respond identically to the same cytotoxic drugs. Although factors such as drug delivery and host-tumour interactions must play a role in this, other factors, in particular intrinsic drug sensitivity must also be important.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Thomas (D.G.T.), Darling (J.L.), Freshney (R.I.), Morgan (D.): In vitro chemosensitivity assay of human glioma by scintillation autofluorography. In: Paoletti P., Walker M.D., Butti G.H. and Knerich R. eds, Multidisciplinary Aspects of Brain Tumor Therapy. Amsterdam, Elsevier, 19–35, (1983).
Morgan (D.), Freshney (R.I.), Darling (J.L.), Thomas (D.G.T.), Celik (F.): Assay of anticancer drugs in tissue culture: Cell cultures of biopsies from human astrocytoma. Br. J. Cancer 47: 205–214 (1983).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 Martinus Nijhoff Publishers, Dordrecht
About this chapter
Cite this chapter
Darling, J.L., Thomas, D.G.T. (1987). Assay of Anticancer Drugs in Tissue Culture: The Effect of Cell Kinetics and the Mode of Action of Drugs on the Chemosensitivity of Cultures Derived from Malignant Brain Tumours. In: Chatel, M., Darcel, F., Pecker, J. (eds) Brain Oncology Biology, diagnosis and therapy. Developments in Oncology, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3347-7_66
Download citation
DOI: https://doi.org/10.1007/978-94-009-3347-7_66
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8003-3
Online ISBN: 978-94-009-3347-7
eBook Packages: Springer Book Archive