Abstract
Xenografts in nude mice allow the study of intrinsic sensitivity of tumor cells to cytotoxic therapies in a threedimensional assembly, similar to that in the original tumor. The good correlation between the chemotherapeutic response of xenografts and the tumor in the patient, which validates the model, has been previously outlined (1). The present study was performed in order to evaluate the response of xenografted astrocytomas to different fractionation regimes and to estimate the repair factor a/b.
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© 1987 Martinus Nijhoff Publishers, Dordrecht
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Bamberg, M., Stuschke, M., Budach, V., Sack, H., Lufen, S. (1987). Human High-Grade Gliomas Grafted into Nude Mice: A Model System to Compare Radiotherapy Schedules. In: Chatel, M., Darcel, F., Pecker, J. (eds) Brain Oncology Biology, diagnosis and therapy. Developments in Oncology, vol 52. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3347-7_61
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DOI: https://doi.org/10.1007/978-94-009-3347-7_61
Publisher Name: Springer, Dordrecht
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