Abstract
The diagnosis of neurological disease has been revolutionized by the advance of threedimensional imaging techniques, especially X-ray computed tomography (CT). With this technique it became possible for the first time to visualize the location and size of a lesion in the brain and to discriminate among various types of brain damage, e.g., tumor, infarction or hemorrhage. In many instances, however, CT as a modality to image morphology does not contribute to the understanding of pathophysiologic mechanisms and cannot be applied for the assessment of therapeutic effects on altered physiologic parameters. For that purpose nuclear medicine techniques can be used which are able to estimate various physiologic variables regionally in the brain. As a disadvantage of these modalities imaging function rather than morphology of brain tissue the coarse spatial resolution inherent to all isotope techniques when compared to CT and magnetic resonance imaging (MRI) of protons must be accepted. The main demand on nuclear medicine techniques must therefore be the quantitation of physiologic and pathologic processes which are necessary for the understanding of pathophysiology of lesions visualized by modalities imaging morphology.
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© 1987 ECSC, EEC, EAEC, Brussels-Luxembourg
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Heiss, WD. (1987). Introduction. In: Heiss, WD., Pawlik, G., Herholz, K., Wienhard, K. (eds) Clinical efficacy of positron emission tomography. Developments in Nuclear Medicine, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3345-3_1
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DOI: https://doi.org/10.1007/978-94-009-3345-3_1
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