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Pharmacokinetics of antiarrhythmic drugs

  • Chapter
Ventricular Tachycardias

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 71))

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Abstract

A knowledge of the pharmacokinetics of antiarrhythmic drugs is most useful for cardiologists dealing with this group of drugs, which have relatively narrow therapeutic ratio. The complex processes of drug disposition in the body, including absorption, distribution and elimination, are the determinants of the drug plasma concentration. These determinants should be systematically considered in order to allow a better therapeutic efficacy, with less risk of toxicity, in patients with heart disease.

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Author information

Authors and Affiliations

  1. Unité de Pharmacologie Clinique Hôpital Saint-Antoine, Paris, France

    Patrice Jaillon

Authors
  1. Patrice Jaillon
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Editor information

Editors and Affiliations

  1. Department of Cardiology, Hôpital Central, Nancy, France

    Etienne Aliot MD, F.A.C.C. (Professor of cardiology) (Professor of cardiology)

  2. Department of Cardiology, Veterans Administration Medical Center and University of Oklahoma Health Center, Oklahoma City, Oklahoma, USA

    Ralph Lazzara MD, F.A.C.C. (Professor of cardiology) (Professor of cardiology)

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© 1987 Martinus Nijhoff Publishers, Dordrecht

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Jaillon, P. (1987). Pharmacokinetics of antiarrhythmic drugs. In: Aliot, E., Lazzara, R. (eds) Ventricular Tachycardias. Developments in Cardiovascular Medicine, vol 71. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3323-1_24

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  • DOI: https://doi.org/10.1007/978-94-009-3323-1_24

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7992-1

  • Online ISBN: 978-94-009-3323-1

  • eBook Packages: Springer Book Archive

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