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Quantitative Contrast Echocardiography: What can the Practicing Cardiologist expect?

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Digital Techniques in Echocardiography

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 64))

Abstract

The contrast echocardiographic effect was first noted by Joyner and first reported by Gramiak and Shah in 1968 [1]. Initially it was used in a largely qualitative manner to answer clinical questions about structure identification, intracardiac shunts, valvular regurgitation, and complex congenital heart disease. These topics have been extensively reviewed [2–6] and will not be covered in this chapter. Suffice it to point out that these initial contrast uses involved answering ‘yes-no’ questions: ‘Does an ASD exist?’, ‘Is this structure the left main coronary artery?’, ‘Does this baby have a PDA’, etc.

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References

  1. Gramiak R, Shah PM: Echocardiography of the aortic root. Invest Radiol 1968; 3: 356–66.

    Article  PubMed  CAS  Google Scholar 

  2. Seward JB, Tajik AJ, Hagler DJ, Ritter DG: Peripheral venous contrast echocardiography. Am J Cardiol 1977; 39: 202–12.

    Article  PubMed  CAS  Google Scholar 

  3. Sahn DJ, Allen HD, George W, Mason M, Goldberg SJ: The utility of contrast echocardiographic techniques in the care of critically ill infants with cardiac and pulmonary disease. Circulation 1977; 56: 599–603.

    Google Scholar 

  4. Meltzer RS, Roelandt J (eds): Contrast Echocardiography. The Hague: Martinus Nijhoff, 1982.

    Google Scholar 

  5. Nanda N: Contrast echocardiography. In: Yu PN, Goodwin JF (eds): Progress in Cardiology. Philadelphia: Lea & Febiger, 1979: 133–45.

    Google Scholar 

  6. Corday E, Shah PN, Meerbaum S (guest editors): Seminar on contrast two-dimensional echocardiography. J Am Coll Cardiol 3: 1–5 & ff., 1984–5.

    Google Scholar 

  7. Meltzer RS, Vered Z, Roelandt J, Neufeld HN: Systematic analysis of contrast echocardiograms. Am J Cardiol 1983; 52: 375–80.

    Article  PubMed  CAS  Google Scholar 

  8. Lieppe W, Behar VS, Scallion R, Kisslo JA: Detection of tricuspid regurgitation with two- dimensional echocardiography and peripheral vein injections. Circulation 1978; 57: 128–33.

    PubMed  CAS  Google Scholar 

  9. Meitzer RS, van Hoogenhuyze DCA, Serruys PW, Haalebos MMP, Hugenholtz PG, Roelandt J: The diagnosis of tricuspid regurgitation by contrast echocardiography. Circulation 1981; 63:1093–99.

    Article  Google Scholar 

  10. Wise NK, Meyers S, Fraker TD, Steward JA, Kisslo JA: Contrast M-mode ultrasonography of the inferior vena cava. Circulation 1981; 63: 1100–1103.

    Article  PubMed  CAS  Google Scholar 

  11. Levin AR, Spach MS, Canent RV, Boineau JP, Capp MP, Jain V, Barr RC: Intracardiac pressure-flow dynamics in isolated ventricular septal defects. Circulation 1967; 35: 430–41.

    PubMed  CAS  Google Scholar 

  12. Serwer GA, Armstrong BE, Anderson PAW, Sherman D, Benson W, Edwards SB: Use of contrast echocardiography for evaluation of right ventricular hemodynamics in the presence of ventricular septal defects. Circulation 1978; 58: 327–36.

    PubMed  CAS  Google Scholar 

  13. Kronik G: Contrast echocardiography in patent foramen ovale. In: Meitzer RS, Roelandt J (eds): Contrast Echocardiography. The Hague: Martinus Nijhoff, 1982: 137–52.

    Chapter  Google Scholar 

  14. Mortera C, Hunter S, Tynan M: Contrast echocardiography and the suprasternal approach in infants and children. Eur J Cardiol 1979; 9: 437–54

    PubMed  CAS  Google Scholar 

  15. Tsuyuguchi N, Nohara R, Suwo M, Yoshimatsu S, Tamagawa M, Shigeta H, Hashimoto M, Kaneko R: Evaluation of cardiac function by contrast echo disappearance time. J Cardiography 1981; 11: 467–75.

    CAS  Google Scholar 

  16. Meitzer RS, Vered Z, Benjamin P, Hegesh J, Visser CA, Neufeld HN: Diagnosing tricuspid regurgitation by direct imaging of the regurgitant flow in the right atrium using contrast echocardiography. Am J Cardiol 1983; 52: 1050–53.

    Article  Google Scholar 

  17. Meitzer RS, Vered Z, Hegesh J, Benjamin P. Visser CA, Shem-Tov A, Neufeld HN: Diagnosis of pulmonic regurgitation by contrast echocardiography. Am Heart 1984; 107: 102–7.

    Article  Google Scholar 

  18. Levine RA, Teichholz LE, Goldman ME, Steinmetz MY, Baker M, Meitzer RS: Microbubbles have intracardiac velocities similar to red blood cells. J Am Coll Cardiol 1984; 3: 28–33.

    Article  PubMed  CAS  Google Scholar 

  19. Zeiher AM, Bonzel T, Wollschlager H, Just J: Diagnostic value of quantitative contrast M-mode echocardiography at the pulmonary valve. Submitted to J Am Coll Cardiol.

    Google Scholar 

  20. Feinstein SB, ten Cate FJ, Zwehl W, Ong K, Maurer G, Tei C, Shah PM, Meerbaum S, Corday E: Two dimensional contrast echocardiography. I. In vitro development and quantitative analysis of echo contrast agents. J Am Coll Cardiol 1984; 3: 14–20.

    Article  PubMed  CAS  Google Scholar 

  21. Smith MD, Kwan OL, Reiser HJ, Daria AN: Superior intensity and reproducibility of SHU-454, a new right heart contrast agent. J Am Coll Cardiol 1984; 3: 992–8.

    Article  PubMed  CAS  Google Scholar 

  22. Meitzer RS, Klig V, Teichholz LE: Generating precision microbubbles for use as an echocardiography contrast agent. J Am Coll Cardiol 1985; 5: 978–82.

    Article  Google Scholar 

  23. Meitzer RS, Koenig K, Klig V, Teichholz LE: Effect of viscosity on the size of microbubbles generated for use as echo contrast agents. Submitted to the American Heart Association, 58th scientific session, (abstract).

    Google Scholar 

  24. Zwehl W, Areeda J, Schwartz G, Feinstein S, Ong K, Meerbaum S: Physical factors influencing quantitation of two-dimensional contrast echo amplitudes. J Am Coll Cardiol 1984; 4: 157–64.

    Article  PubMed  CAS  Google Scholar 

  25. Ong K, Maurer G, Feinstein S, Zwehl W, Meerbaum S, Corday E: Computer methods for myocardial contrast two-dimensional echocardiography. J Am Coll Cardiol 1984; 3: 1212–8.

    Article  PubMed  CAS  Google Scholar 

  26. DeMaria AN, Bommer WJ, Riggs K et al.: Echocardiographic visualization of myocardial perfusion by left heart and intracoronary injections of echo contrast agent. Circulation 1980; 60 (Suppl. III): III-143 (abstract).

    Google Scholar 

  27. Armstrong W, Mueller T, Kinney E, Thickner G, Dillon J, Feigenbaum H: Assessment of myocardial perfusion abnormalities with contrast enhanced two-dimensional echocardiography. Circulation 1982; 66: 166–74.

    Article  PubMed  CAS  Google Scholar 

  28. Meitzer RS, Vermeulen HW, Valk N, Verdouw P, Lancee CT, Roelandt J: New echocardiographic contrast agents: transmission through the lungs and myocardial perfusion imaging. J Cardiovasc Ultrasonography 1982; 1:277–82

    Google Scholar 

  29. Goldman ME, Mindich BP: Intraoperative cardioplegic contrast echocardiography for assessing myocardial perfusion during open heart surgery. J Am Coll Cardiol 1984; 5: 1029–34

    Article  Google Scholar 

  30. Santoso T, Roelandt J, Mansjoer H, Abdurahman M, Meitzer RS, Hugenholtz PG: Use of polygelin colloid solution for contrast echocardiographic myocardial perfusion imaging in humans. J Am Coll Cardiol (in press).

    Google Scholar 

  31. Sakamaki T, Tei C, Meerbaum S, Shimoura K, Kondo S, Fishbein MC, Y-Rit J, Shah PM, Corday E: Verification of myocardial contrast two-dimensional echocardiographic assessment of perfusion defects in ischemic myocardium. J Am Coll Cardiol 1984; 3: 34–8.

    Article  PubMed  CAS  Google Scholar 

  32. Tei C, Kondo S, Meerbaum S, Ong K, Maurer G, Wood F, Sakamaki T, Shimoura K, Corday E, Shah PM: Correlation of myocardial echo contrast disappearance rate (’washout’) and severity of experimental coronary stenosis. J Am Coll Cardiol 1984; 3: 39–46.

    Article  PubMed  CAS  Google Scholar 

  33. Ten Cate FJ, Drury JK, Meerbaum S, Noordsy J, Feinstein S, Shah PM: Myocardial contrast two- dimensional echocardiography: experimental examination at different coronary flow levels. J Am Coll Cardiol 1984; 3: 1219–26.

    Article  PubMed  Google Scholar 

  34. Kondo S, Tei C, Meerbaum S, Corday E, Shah PM: Hyperemic response of intracoronary contrast agents during two-dimensional echographic delineation of regional myocardium. J Am Coll Cardiol 1984; 4: 149–56.

    Article  PubMed  CAS  Google Scholar 

  35. Bommer WJ, Shah PM, Allen H, Meitzer R, Kisslo J: The safety of contrast echocardiography: report of the committee on contrast echocardiography for the American Society of Echocardiography. J Am Coll Cardiol 1984; 3: 6–13

    Article  PubMed  CAS  Google Scholar 

  36. Gillam LD, Kaul S, Fallon JT, Hedley-White ET, Slater CE, Weyman AE: Sequelae of echocardiographic contrast: studies of myocardium, brain, and kidney. Circulation 1984; 70 (Suppl. II): 11–6 (abstract).

    Google Scholar 

  37. Holt G, Reeves W, Rieder M, Daley L, Murthy V, Christensen C: Negative inotropic effects of intracoronary echo-contrast agents. J Am Coll Cardiol 1985; 5: 474 (abstract).

    Google Scholar 

  38. Levine RA, Gillam LD, Guerrero JL, Weyman AE: Wall motion abnormalities following myocardial echo contrast injection are caused by microbubbles. J Am Coll Cardiol 1985; 5: 474 (abstract).

    Google Scholar 

  39. Hagler DJ, Tajik AJ, Seward JB, Mair DD, Ritter DG, Ritman EL: Videodensitometric quantitation of left-to-right shunts with contrast sector echocardiography. Circulation 1978; 58 (Suppl. II): 11–70 (abstract).

    Google Scholar 

  40. Hagler DJ, Tajik AJ, Seward JB, Ritman EL, in: Meitzer RS, Roelandt J (eds): Contrast Echocardiography. The Hague: Martinus Nijhoff, 1982: 298–303.

    Chapter  Google Scholar 

  41. Serwer GA, Armstrong BE, Anderson PAW, Sherman D, Benson DW, Edwards SB: Use of contrast echocardiography for evaluation of right ventricular hemodynamics in the presence of ventricular septal defects. Circulation 1978; 58: 327

    PubMed  CAS  Google Scholar 

  42. Serwer GA, Armstrong BE: Contrast echocardiography for evaluation of right ventricular hemodynamics in the presence of ventricular septal defects In: Meitzer RS, Roelandt J (eds). Contrast Echocardiography. The Hague: Martinus Nijhoff, 1982: 179–91.

    Chapter  Google Scholar 

  43. Valdes-Cruz LM, Sahn DJ: Ultrasonic contrast studies for the detection of cardiac shunts. J Am Coll Cardiol 1984; 3: 978–85.

    Article  PubMed  CAS  Google Scholar 

  44. Meitzer RS, Bastiaans OL, Lancee CT, Pierard L, Serruys PW, Roelandt J: Videodensitometric processing of contrast two-dimensional echocardiographic data. Ultrasound in Med & Biol 1982; 8: 509–14

    Article  Google Scholar 

  45. Bommer WJ, Neef J, Neuman A, Weinert L, Lee G, Mason DT, Daria AN: Indicatordilution curves obtained by photometric analysis of two-dimensional echo-contrast studies. Am J Cardiol 1978; 41: 370 (abstract).

    Article  Google Scholar 

  46. DeMaria AN, Bommer W, Kwan OL, Riggs K, Smith M, Waters J: In vivo correlation of thermodilution cardiac output and videodensitometric indicator-dilution curves obtained from contrast two-dimensional echocardiograms J Am Coll Cardiol 1984; 3: 999–1004.

    Article  PubMed  CAS  Google Scholar 

  47. Tickner EG Precision microbubbles for right-sided intracardiac pressure and flow measurements. In: Meitzer RS, Roelandt J (eds): Contrast Echocardiography. The Hague: Martinus Nijhoff, 1982: 313–24.

    Chapter  Google Scholar 

  48. Sahn DJ, Valdes-Cruz LM, Jones M, Main J, Swensson RE, Elias W, Eidbo E, Gerber KH: Contrast echocardiographic quantitation of aortic insufficiency: studies in an animal model using a standardized experimental echo contrast agent. J Am Coll Cardiol 1984; 3: 563 (abstract).

    Article  Google Scholar 

  49. Bloomfield DA (ed), Dye Curves. Baltimore: University Park Press, 1974.

    Google Scholar 

  50. Prof. VL Newhouse, Philadelphia, PA — personnal communication

    Google Scholar 

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Author information

Authors and Affiliations

  1. Sinai Medical Center, New York, USA

    Richard S. Meltzer

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  1. Richard S. Meltzer
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Editors and Affiliations

  1. Thoraxcenter, Erasmus University, Rotterdam, The Netherlands

    J. Roelandt

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© 1987 Martinus Nijhoff Publishers, Dordrecht

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Meltzer, R.S. (1987). Quantitative Contrast Echocardiography: What can the Practicing Cardiologist expect?. In: Roelandt, J. (eds) Digital Techniques in Echocardiography. Developments in Cardiovascular Medicine, vol 64. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3307-1_5

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  • DOI: https://doi.org/10.1007/978-94-009-3307-1_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7985-3

  • Online ISBN: 978-94-009-3307-1

  • eBook Packages: Springer Book Archive

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