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Gastrointestinal Campylobacter-Like Organisms

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Recent Advances in Anaerobic Bacteriology

Part of the book series: New Perspectives in Clinical Microbiology ((NPCM,volume 12))

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Abstract

Campylobacter jejuni, the aetiological agent of 5–10% of episodes of diarrhoea in North America and Europe is described and its relatives C. coli and C. laridis are mentioned; and are compared with C. fetus. The predilection of campylobacters for immuno-compromised hosts is discussed.

Organisns similar to these and called campylobacterlike (CLO) have been described recently. C. ‘pyloridis’ or G.CLO-1, the best known, is isolated from the antrum of the stomach in close association with gastritis and gastric and duodenal ulcers. Its properties are compared with those of C. jejuni. Another stomach isolate in association with gastritis is G.CLO-2. From hypogammaglobulinaemic patients an organism very similar to C. ‘pyloridis’ has been found. This differs in being resistant to erythromycin. It also produces less acidic mucosubstance in vitro than does C. ‘pyloridis’, whereas G.CLO-2 produces a similar amount and C. jejuni none. C. ‘cinaedi’ and C. ‘fennelliae’ have been isolated from rectal biopsies of male patients with proctitis and diarrhoea and C. ‘cinaedi’ from the blood of immunecompromised male homosexuals. C. ‘hyointestinalis’ isolated from prolifer-ative enteritis in pigs is the only facultative anaerobe, all the other organisms described as being microaerophilic. Plating of filtered specimens onto antibiotic-free media have yielded other CLOs associated with diarrhoea.

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Authors and Affiliations

  1. Division of Communicable Diseases, Clinical Research Centre, HA1 3UJ, Harrow, Middlesex, UK

    Jean M. Dolby

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  1. Jean M. Dolby
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Editor information

Editors and Affiliations

  1. Division of Communicable Diseases, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, England

    S. P. Borriello

  2. Department of Oral Microbiology, The London Hospital Medical College, Turner Street, E1 2AD, London, UK

    J. M. Hardie

  3. London School of Hygiene and Tropical Medicine, Keppel Street, London, UK

    B. S. Drasar

  4. Department of Medical Microbiology, University of Sheffield Medical School, Beech Hill Road, S10 2RX, Sheffield, UK

    B. I. Duerden

  5. Bacterial Metabolism Research Laboratory, PHLS Centre for Applied Microbiology and Research, Porton Down, SP4 OJG, Salisbury, Wilts, UK

    M. J. Hudson

  6. Institute for Research on Animal Diseases, Compton, Berkshire, UK

    R. J. Lysons

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© 1987 Martinus Nijhoff Publishers, Dordrecht

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Dolby, J.M. (1987). Gastrointestinal Campylobacter-Like Organisms. In: Borriello, S.P., Hardie, J.M., Drasar, B.S., Duerden, B.I., Hudson, M.J., Lysons, R.J. (eds) Recent Advances in Anaerobic Bacteriology. New Perspectives in Clinical Microbiology, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3293-7_5

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  • DOI: https://doi.org/10.1007/978-94-009-3293-7_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7978-5

  • Online ISBN: 978-94-009-3293-7

  • eBook Packages: Springer Book Archive

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