Abstract
Within the framework of preclinical safety testing a compound having cardiovascular activity (CC), was studied in rabbits. For the study of its teratogenic potential, CC was administered orally to Dutch rabbits from day 6 to 18 of pregnancy at dose levels of 25, 50 and 100 mg/kg body weight.
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References
Z. Klin. Chem. Klin. Biochem. 15, 249–51, 1977
Z. Klin. Chem. Klin. Biochem. 10, 281–91, 1972
Pearce, J., Br. Med. J. 2, 167, 1965
Aoki, T., Namiki, H. and Tokudome, S. Jap. J. Alcohol Stud. Drug Depend. 17, 226–36, 1982.
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© 1988 Martinus Nijhoff Publishers, Dordecht
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Yih, T.D., Degen, A.J.M., Kamerman, J., Joosten, H.F.P. (1988). The Dutch Rabbit in Toxicity Testing Chemical — Induced Creatine Kinase Release; a Species- and Strain-Specific Response?. In: Beynen, A.C., Solleveld, H.A. (eds) New Developments in Biosciences: Their Implications for Laboratory Animal Science. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3281-4_36
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DOI: https://doi.org/10.1007/978-94-009-3281-4_36
Publisher Name: Springer, Dordrecht
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