Skip to main content

Gene Mapping and Linkage Homology

  • Chapter

Abstract

Information on the linkage map of laboratory animals is of value for the genetic quality control of inbred strains. A reliable method for genetic monitoring is provided by the characterization of inbred strains for a given set of monogenic markers and the regular control of this genetic profile. The marker genes used for this system should be sufficiently distributed among the genome.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bailey DW: Recombinant-inbred strains. An aid to identify linkage and function of histocompatibility and other genes. Transplantation 11, 325–327, 1971.

    Google Scholar 

  2. Bender K, Nagel M and Günther E: atEs-6, a further polymorphie esterase in the rat. Biochem Genet 20, 221–228, 1982.

    Article  PubMed  CAS  Google Scholar 

  3. Deimling O von: MNL 68, 65–66, 1983.

    Google Scholar 

  4. Deimling O von: Esterase-23 (Es-23): Characterization of a new carboxylesterase isozyme (EC 3.1.1.1) of the house mouse, genetically linked to Es-2 on chromosome 8. Biochem Genet 22, 769–782, 1984.

    Article  Google Scholar 

  5. Deimling O von; pers comm 1987.

    Google Scholar 

  6. Demant P Hart AAM: Recombinant congeanic strains. A new tool for analyzing genetic traits determined by more than one gene. Immunogenetics 24, 416–422, 1986.

    Article  PubMed  CAS  Google Scholar 

  7. Fox RR and Van Zutphen LFM: Chromosomal homology of rabbit (Oryctolagus cuniculus) linkage group VI with rodent species. Genetics 22, 183–189, 1979.

    Google Scholar 

  8. Gasser DL, Silvers WK, Reynolds HM, Black G and Palm J: Serum esterase genetics in rats: two new alleles at Es-2, a new esterase regulated by hormonal factors and the linkage of these loci to the Ag-C blood group locus. Biochem Genet 10, 207–217, 1973.

    Article  PubMed  CAS  Google Scholar 

  9. Hedrich HJ and Von Deimling: Re-evaluation of linkage group 4 of the rat and assignment of twelve carboxylesterases to two gene clusters. J Hered 1987 (in press).

    Google Scholar 

  10. Lalley PA and McKusick VA: Report of the committee en comparative mapping. Cytogen Cell Genet 40, 536–566, 1985.

    Article  CAS  Google Scholar 

  11. Mentlein R,Ronai A, Robbi M, Heymann E and Von Deimling O: Genetic identification of rat liver carboxylesterases (EC 3.1.1.1) isolated in different laboratories. Arch Bioch Bioph (in press) 1987.

    Google Scholar 

  12. Nash HR and Von Deimling O: Kidney esterases of Mus muscules: Further polymorphism of esrase, esterase-20. Biochem Genet 20, 537–554, 1982.

    Article  PubMed  CAS  Google Scholar 

  13. Otto J and Von Deimling O: Esterase-17 (Es-17): Characterization and linkage to chromoshosphate resistant esterase of the house mouse (Mus musculus). Biochem Genet 21, 37–48, 1983.

    Article  PubMed  CAS  Google Scholar 

  14. Peters J: Non-specific esterase of Mus musculus. Biochem Genet 20, 585–606, 1992

    Article  Google Scholar 

  15. Peters Jand Nash HR: Esterase of Mus musculus: Substrate and inhibition charactgies with man. Biochem Genet 16, 553–563, 1978.

    Article  PubMed  CAS  Google Scholar 

  16. Scholze M Günther E and Von Deimling O: Esterase-13 of the rat (Rattus norvegicus of the house mouse (Mus musculus). Comp Biochem Physiol 78B, 713–718, 1984.

    CAS  Google Scholar 

  17. Searle AG: Clues to homologous regions in mammalian autosomes. Cytogenet Cell Genet 6, 430–435, 1976.

    Article  Google Scholar 

  18. Womack JE and Sharp M: Comparative autosomal linkage in mammels: Genetics of esterases in Mus musculus and Rattus norvegicus. Genetics 8, 665–675, 1976.

    Google Scholar 

  19. Zutphen LFM van, Den Bieman MGCW and Bouw J: Serum esterase genetics in rabbits. IV The prealbumin and (5-globulin systems. Biochem Genet 15, 989–1000, 1977.

    Article  PubMed  Google Scholar 

  20. Zutphen LFM van, Fox RR and Den Bieman MGCW: Genetics of two tissue esterase polymorphims (Est-4 and Est-5) in the rabbit. Biochem Genet 2A, 773–780, 1983.

    Article  Google Scholar 

  21. Zutphen LFM van: Genetics of laboratory Animals. In: Laboratory Animals. World Animal Science C2. EJ Ruitenberg and PJW Peters (eds). Elsevier Science Publishers, Amsterdam 1986, pp 47–84.

    Google Scholar 

  22. Zutphen LFM van and Den Bieman MGCW: Unpubl. results, 1987.

    Google Scholar 

  23. Zutphen LFM van, Den Bieman MGCW and Koster A: Esterase genetics and clofibrate hydrolysis in rat and rabbit. Z Versuchst k 1987 (in press)

    Google Scholar 

  24. Zutphen LFM van, Den Bieman MGCW, Von Deimling O and Fox RR: Genetics of a tissue esterase polymorphism (Est-6) in the rabbit (Oryctolagus cuniculus). Biochem Genet 1987 (in press).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Martinus Nijhoff Publishers, Dordecht

About this chapter

Cite this chapter

Van Zutphen, L.F.M., Den Bieman, M.G.C.W. (1988). Gene Mapping and Linkage Homology. In: Beynen, A.C., Solleveld, H.A. (eds) New Developments in Biosciences: Their Implications for Laboratory Animal Science. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3281-4_32

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-3281-4_32

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7973-0

  • Online ISBN: 978-94-009-3281-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics