The Housing and Handling of Marmosets and Tamarins Infected with Aids and Other Retroviruses
In the search for suitable animal models for AIDS and other retrovirus infections it was proposed to infect the common marmoset, Callithrix jacchus, and the cotton-topped tamarin, Saguinus oedipus, with the viruses HIV-1 , HIV-2, HTLV-1 and HTLV-2. To comply with the Guidelines issued in the United Kingdom by the Advisory Committee on Dangerous Pathogens the work has to be undertaken at Animal Containment Level 3 (Health and Safety Executive, 1984; 1986). Scratches or bites from animals inoculated with AIDS and similar viruses must be regarded as a potential hazard to staff and the normal method of handling these animals was considered unacceptable. Normally, they would be caught by putting a leather-gloved hand into the cage and holding the animal around the shoulders. To avoid handling the animal in this manner a cage was designed to minimise risks from bites and scratches, and to enable the animal to be trapped safely in a nest box with a crush-back facility.
KeywordsCommon Marmoset Guillotine Door Suitable Animal Model Safety Executive Dangerous Pathogen
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