Abstract
A common approach to the analysis of complex phenomena is to develop a model which parallels the salient features of the subject of investigation, but which is more amenable to experimental dissection and manipulation. The International Union against Cancer (UICC) recognises over 200 distinct neoplastic diseases1; individuals vary enormously in their susceptibility to different types of cancer, in the rate of progression of their diseases, and in their responses to treatment. In the case of animal models of cancer(s) in man, therefore, a fundamental problem lies in the sheer diversity of phenomena which we wish to understand.
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Eccles, S.A. (1987). Animal models of cancer. In: Waring, M.J., Ponder, B.A.J. (eds) Biology of Carcinogenesis. Cancer Biology and Medicine, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3213-5_6
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