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A clinical perspective on hepatic regeneration

  • A. L. Baker
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Abstract

Despite continuing study, uncertainty persists about the basic mechanisms underlying hepatic regeneration. A growing body of evidence suggests that circulating hormones and other growth promoting factors are involved in the process, but there is less information about how these substances bind to hepatocyte membrane and initiate intracellular signals resulting in DNA synthesis and cell proliferation. The purpose of this review is to summarize recent studies which shed light on some of the processes involved in hepatic regeneration and to highlight the clinical studies which have attempted to apply these principles to the treatment of patients with liver disease.

Keywords

Liver Regeneration Partial Hepatectomy Fulminant Hepatic Failure Alcoholic Hepatitis Hepatic Regeneration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© MTP Press Limited 1987

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  • A. L. Baker

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