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Emotional, Clinical, and Familial Correlates of Antisocial Personality Disorder and Alcoholism in Men with Unipolar Major Depression

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Biological Contributions to Crime Causation

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Abstract

The assessment of the clinical and emotional correlates of alcoholism is important for understanding more about the disease process itself. Investigators have reported at least two factors which predispose to problem drinking; they are: a psychiatric diagnosis of antisocial personality (ASP) (Lewis, Cloninger, & Pais, 1983; Lewis, Rice, and Helzer, 1983b; Lewis, Robins, & Rice, 1985), and a family history of alcoholism (Cotton, 1979). Furthermore, half sibling (Schuckit, Goodwin, & Winokur, 1972) and adoption (Cloninger, Bohman, and Zigvardsson, 1981; Goodwin, Schulsinger, Hermansen, Guze, & Winokur, 1973) studies have demonstrated that this familial disposition may pass from one generation to another in the absence of being raised by alcoholic parents. Our studies (Lewis, et al., 1983b; 1985b) indicate that both a diagnosis of ASP and a positive family history make independent contributions to increase the risk of alcoholism.

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Lewis, C.E., Rice, J., Andreasen, N., Endicott, J., Hartman, A. (1988). Emotional, Clinical, and Familial Correlates of Antisocial Personality Disorder and Alcoholism in Men with Unipolar Major Depression. In: Moffitt, T.E., Mednick, S.A. (eds) Biological Contributions to Crime Causation. NATO ASI Series, vol 40. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2768-1_16

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  • DOI: https://doi.org/10.1007/978-94-009-2768-1_16

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