Abstract
While there is no dearth of writing about ethical issues regarding human experimentation in the literature of bioethics, surprisingly little has been written, particularly in recent years, about the question of whether or not any type of obligation might exist to participate in medical research. Most contemporary discussions focus on the adequacies and inadequacies of informed consent in combination with institutional peer review boards in protecting the welfare of subjects against abuse by researchers. Or, to put the point more accurately, the discussion of the ethics of research involving human beings currently consists of adversarial haggling about the details of specific legal and regulatory provisions concerning exactly what research must be reviewed, who is competent to consent, who ought to do the reviewing of experimental protocols, and exactly what degree of detail makes for a truly informed consent [20].
I would like to thank Janet Caplan, Hans Jonas, Ronald Bayer, John Arras, and Anthony E. Gallo, Jr., for their helpful comments on an earlier draft of this essay. I would also like to thank the members of the Hastings Center staff and the philosophy department at Union College for their comments and suggestions when this paper was presented as an invited address. Finally, I would like to acknowledge the support of the Charles C. Culpeper Foundation in preparing this manuscript.
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Bibliography
Alexander, L.: 1949, ‘Medical Science Under Dictatorship’, New England Journal of Medicine 241, 39–47.
Arneson, R. J.: 1982, ‘The Principle of Fairness and Free-Rider Problems’, Ethics 92, 616–633.
Arras, J. and Hunt, R. (eds.): 1983, Ethical Issues in Modern Medicine (2nd ed.), Mayfield Press, Palo Alto, California.
Barber, B. et al.: 1973, Research on Human Subjects, Russell Sage, New York.
Beecher, H. K.: 1966, ‘Ethics and Clinical Research’, New England Journal of Medicine 274, 1354–1360.
Beecher, H. K.: 1970, Research and the Individual, Appendix A, Little Brown and Co., Boston, Massachusetts.
Carmi, A. (ed): 1979, ‘The Challenge of Experimentation’, in Medical Experimentation, Turtledove Press, Ramat-Gan, Israel.
Chalmers, T.C., et al.: ‘Controlled Studies in Clinical Cancer Research’, New England Journal of Medicine 287, 75–78.
Cooke, R. A.: 1980, ‘Some Notes on the Subjects of Biomedical and Behavioral Research’, Report prepared for the President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research, U.S. Government Printing Office, Washington, D.C.
Eisenberg, L.: 1977, ‘The Social Imperatives of Medical Research’, Science 198, 1105–1110.
Fishkin, J.: 1982, The Limits of Obligation, Yale University Press, New Haven, Connecticut.
Freund, P. A. (ed.): 1970, Experimentation with Human Subjects, George Braziller, Inc., New York.
Fried, C.: 1974, Medical Experimentation, Elsevier, New York.
Hart, H. L. A.: 1955, ‘Are There Any Natural Rights?’, Philosophical Review 64, reprinted in A. Melden (ed), Human Rights (1977), Wadsworth Publishing Co., Belmont, California, pp. 61–75.
Jonas, H.: 1970, ‘Philosophical Reflections on Experimenting with Human Subjects’, in P. Freund (ed.), Experimentation with Human Subjects, George Braziller, New York.
Katz, J.: 1972, Experimentation with Human Beings, Russell Sage Foundation, New York.
McCormick, R.: 1974, ‘Proxy Consent in the Experimental Situation’, Perspectives in Biology and Medicine 18, 2–20.
Muggia, F. M.: 1981, ‘Anticancer Drug Development and Federal Regulation: Protection Against Progress?’, American Journal of Medicine 71, 341–344.
Nozick, R.: 1974, Anarchy, State and Utopia, Basic Books, New York.
President’s Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research: 1983, Implementing Human Research Regulations, U.S. Government Printing Office, Washington, D.C.
Rawls, J.: 1971, A Theory of Justice, Harvard University Press, Cambridge, Massachusetts.
Rosenthal, R. and Rosnow, R. L.: 1975, The Volunteer Subject, John Wiley and Sons, New York.
Simmons, A. J.: 1979, Moral Principles and Political Obligations, Princeton University Press, Princeton, New Jersey.
Smith, C., et al.: 1983, ‘Drug Trials, the Elderly, and the Very Aged’, Lancet 266, 1139.
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Caplan, A.L. (1988). Is There an Obligation to Participate in Biomedical Research?. In: Spicker, S.F., Alon, I., de Vries, A., Engelhardt, H.T. (eds) The Use of Human Beings in Research. Philosophy and Medicine, vol 28. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2705-6_12
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DOI: https://doi.org/10.1007/978-94-009-2705-6_12
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