Abstract
The ability of the pathologist to classify malignant neoplasms has improved dramatically in the past two decades with the expanded application of immunocytochemical staining procedures and electron microscopy to the study of tumors. The roles of these techniques in the evaluation of neoplasms that can not be classified by conventional light microscopy is in part determined by the general category into which a particular tumor falls. Most bone sarcomas can be identified without difficulty from their radiologic appearance and histopathology as seen in paraffin sections. Many soft tissue sarcomas are in contrast difficult to classify by light microscopy alone. The significance to the clinician and his patient of precision in the subclassification of a soft tissue sarcoma is somewhat limited at the present time because there are not many clear-cut differences in behavior among the various subtypes.
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References
Troncoso P, Ordonez NG, Mackay B: Soft tissue tumors. Clin Lab Med 7:249–260, 1987.
Mackay B, Ordonez NG: The role of the pathologist in the evaluation of poorly differentiated tumors and metastatic tumors of unknown origin. In Poorly Differentiated Neoplasms and Tumors of Unknown Origin. Fer MF, Greco FA, Oldham RK (eds.), Florida, Grune and Stratton, pp 3–74, 1986.
Meis JM, Mackay B, Ordonez NG: Epithelioid sarcoma: An immunohistochemical and ultrastructural study. Surg Pathol (in press).
Benson JD, Kraeraer BB, Mackay B: Malignant melanoma of soft parts: An ultrastructural study of four cases. Ultrastruct Pathol 8:57–70, 1985.
Mackay B, Fanning T, Bruner JM, Steglich MC: Diagnostic electron microscopy using fine needle aspiration biopsies. Ultrastruct Pathol 11:659–672, 1987.
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© 1988 Kluwer Academic Publishers
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Mackay, B. (1988). Electron Microscopy of Sarcomas. In: Ryan, J.R., Baker, L.O. (eds) Recent Concepts in Sarcoma Treatment. Developments in Oncology, vol 55. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2691-2_8
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DOI: https://doi.org/10.1007/978-94-009-2691-2_8
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7714-9
Online ISBN: 978-94-009-2691-2
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