Abstract
A Multidisciplinary approach to the management of soft tissue sarcomas has led to improvements in the rates of local control, despite increasing use of limb salvage procedures. However, metastasis, which seems to correlate with higher histological grade, remains a distressingly frequent problem, occurring in approximately 30% of individuals, often in the absence of local failure.
A study conducted by the Soft Tissue & Bone Sarcoma Group of the European Organization for Research and Treatment of Cancer.
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References
Bramwell VHC: The role of chemotherapy in multi-disciplinary treatment. Can J Surg (in press) 1987.
Gottlieb JA, Baker LH, O’Bryan RM, et al.: Adriamycin (NSC–123127) used alone and in combination for soft tissue and bone sarcomas. Cancer Chemother Rep 6:271–282, 1975.
Bramwell VHC, Rouessé J, Santoro A, et al.: European experience of adjuvant chemotherapy for soft tissue sarcoma: a randomized trial comparing CYVADIC with control (preliminary report). Cancer Treat Symposia 3:99–107, 1985.
Rosenberg SA, Chang AE, Glatstein E: Adjuvant chemotherapy for treatment of extremity soft tissue sarcomas: review of the National Cancer Institute Experience. Cancer Treat Symposia 3:83–88, 1985.
Benjamin RS, Terjanian TO, Fenoglio CJ, et al.: The importance of combination chemotherapy for adjuvant treatment of high risk patients with soft tissue sarcomas of the extremities. Adjuvant Therapy of Cancer V, Grune & Stratton, pp. 735–744, 1987.
Edmonson JH, Fleming TR, Ivins JC, et al.: Randomized study of systemic chemotherapy following complete excision of non-osseous sarcomas. J Clin Oncol 2:1390–1396, 1984.
Gherlinzoni F, Bacci G, Picci P, et al.: A randomized trial for the treatment of high grade soft tissue sarcomas of the extremities: preliminary observations. J Clin Oncol 4:552–558, 1986.
Alvegard TA: Adjuvant chemotherapy with Adriamycin in high grade malignant soft tissue sarcoma - A Scandinavian randomized study. Proc Am Soc Clin Oncol 5:125, 1986.
Antman, K, Amato D, Lerner H, et al.: Adjuvant Doxorubicin for sarcoma: Data from the Eastern Cooperative Oncology Group and Dana-Farber Cancer Institute/ Massachusetts General Hospital studies. Cancer Treat Symposia 3:109–116, 1985.
Eilber FR, Giuliano AE, Huth JF, Morton DL: Adjuvant Adriamycin in high grade extremity soft tissue sarcoma -a randomized prospective trial. Proc Am Soc Clin Oncol 5:125, 1986.
Sylvester R: Soft tissue sarcomas of the extremities. J Clin Oncol 5:321–322, 1987.
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© 1988 Kluwer Academic Publishers
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Bramwell, V. et al. (1988). European Experience of Adjuvant Chemotherapy for Soft Tissue Sarcoma: Interim Report of a Randomized Trial of Cyvadic Versus Control. In: Ryan, J.R., Baker, L.O. (eds) Recent Concepts in Sarcoma Treatment. Developments in Oncology, vol 55. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2691-2_24
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DOI: https://doi.org/10.1007/978-94-009-2691-2_24
Publisher Name: Springer, Dordrecht
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