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Proceedings of the Fourth International Symposium on Cyclodextrins pp 293–298Cite as

Increasing the Solubility Characteristics of Iomeglamic Acid with β-Cyclodextrin

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Part of the book series: Advances in Inclusion Science ((AIS,volume 5))

Abstract

Iomeglamic acid has been successfully applied for radioscopy of the gall-bladder since 1972. This phar-macon has the disadvantageous property that is practically insoluble in water:.5.76 mg/100 ml at 22 C. Preparations containing the drug in different concentrations (10%, 30%, 50%, 70% and 90%) were made with β-cyclo dextrin (=β -CD) by different methods (kneading ana spra -embedding) and their dissolution characteristics were de termined.

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References

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Author information

Authors and Affiliations

  1. Department of Drug Technology, P. O. Box 121, H-6701, Szeged, Hungary

    M. Kata & Z. Aigner

  2. Sektion Pharmazie, Weinbergweg 15, DDR-4020, Halle/S., GDR

    F. Fahr

Authors
  1. M. Kata
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  2. Z. Aigner
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  3. F. Fahr
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Editor information

Editors and Affiliations

  1. Consortium für Elektrochemische Industrie GmbH, Munich, Germany

    O. Huber

  2. CHINOIN Pharmaceutical-Chemical Works, Budapest, Hungary

    J. Szejtli

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© 1988 Kluwer Academic Publishers

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Kata, M., Aigner, Z., Fahr, F. (1988). Increasing the Solubility Characteristics of Iomeglamic Acid with β-Cyclodextrin. In: Huber, O., Szejtli, J. (eds) Proceedings of the Fourth International Symposium on Cyclodextrins. Advances in Inclusion Science, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2637-0_43

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  • DOI: https://doi.org/10.1007/978-94-009-2637-0_43

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7690-6

  • Online ISBN: 978-94-009-2637-0

  • eBook Packages: Springer Book Archive

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