Abstract
Heptakis (2,6-di-O-pentyl)-β-CD 1b and heptakis (2,3,6-tri-O-pentyl)-β-CD 2b were synthesized by etherification of β-CD, Acetylation of 1b yielded heptakis (2,6-di-O-pentyl,3-O-acetyl)-β-CD. The corresponding α-CD derivatives were obtained in the same way. All of these compounds are well soluble in most aprotic organic solvents and they are able to complex polar guest molecules. The stability constants of these complexes were measured by an improved Benesi-Hildebrand procedure using NMR data.
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References
Szejtli, J. Cyclodextrins and their Inclusion Complexes, Akademiai Kioado, Budapest 1982.
Croft, A. P.; Bartsch, R. A.; Tetrahedron 39, 1417–74 (1983).
Szejtli, J.; Liptak, A.; Jodal, I.; Fügedi, P.; Nanasi, P.; Neszmelyi, A. Starch 32, 165–9 (1980).
Uekama, K.; Hirashima, N.; Horiuchi, Y.; Hirayama, F.; Ijitsu, T.; Ueno, U.; K. Hirashima, N.; Horiuchi, Y. J.Pharm.Sci. 76, 660-1 (1987).
Menger, F. M.; Dulany, M. A. Tetrahedr. Lett. 26, 267–270 (1985).
Ciucanu, I.; Kerek, F. Carbohydrate Research 131, 209–17 (1984).
A more detailed procedure will be published soon.
Diederich, F. Angew. Chem. 100, 372–96 (1988).
Bevington, P.R. Data Reduction and Error Analysis for the Physical Sciences, Mc Graw Hill New ork, 1969 p.232.
K. Jeffrey Johnson, Numerical Methods in Chemistry, Marcel Dekker, New York 1980, p.278.
The program EXACT FIT is written in BASIC, copies are available from the authors on request.
Benesi, H. A.; Hildebrand, J.H. J. Amer. Chem. Soc. 71, 2703 (1949).
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© 1988 Kluwer Academic Publishers
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Wenz, G., von der Bey, E. (1988). Inclusion Properties of Hydrophobic Derivatives of Cyclodextrins (CDs). In: Huber, O., Szejtli, J. (eds) Proceedings of the Fourth International Symposium on Cyclodextrins. Advances in Inclusion Science, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2637-0_21
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DOI: https://doi.org/10.1007/978-94-009-2637-0_21
Publisher Name: Springer, Dordrecht
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