Abstract
Although less extensively studied than copper, the metabolism of zinc has also been shown to be affected by rheumatoid arthritic conditions, a decrease of plasma zinc concentration being the change most frequently observed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Niedermeier, W and Grigge, JH (1971). Trace metal composition of synovial fluid and blood serum of patients with rheumatoid arthritis. J Chron Dis, 23, 527–36
Sorenson, JRJ and Di Tommaso, DJ (1977). Mean serum copper, magnesium and zinc concentration in active rheumatoid and other degenerative connective tissue disease. In Hemphill, DD (ed.), Trace Substances in Environmental Health, Vol. XI (Columbia: University of Missouri), pp. 15–22
Balogh, Z, El-Gobarey, AF, Fell, GS et al. (1980). Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis. Ann Rheum Dis, 39, 329–32
Morgenstern, H and Machtey, I (1983). Serum zinc and copper levels in rheumatoid arthritis. Arthritis Rheum, 26, 933–4
Svenson, KLG, Hallgren, R, Johansson, E and Lindth, U (1985). Reduced zinc in peripheral blood cells from patients with inflammatory connective tissue diseases. Inflammation, 9, 189–99
Pandey, SP, Bhattacharya, SK and Sundar, S (1985). Zinc in rheumatoid arthritis. Indian J Med Res, 81, 618–20
Bonebrake, RA, McCall, JT, Hunder, GG and Polley, HF (1972). Zinc accumulation in synovial fluid. Mayo Clin Proc, 47, 746–50
Ambanelli, U, Ferraccioli, GF, Bernardi, P and Serventi, G (1978). Relation between urine zinc and hydroxyproline in rheumatoid arthritis and bone disease. J Rheumatol, 5, 477–9
Aaseth, J, Munthe, E, Forre, O and Steinnes, E (1978). Trace elements in serum and urine of patients with rheumatoid arthritis. Scand J Rheumatol, 7, 237–40
Jepsen, LV and Pedersen, KH (1984). Changes in zinc and zinc-dependent enzymes in rheumatoid patients during penicillamine treatment. Scand J Rheumatol, 13, 282–8
Sharma, RP (1983). Metabolism of intracellular zinc and copper following single and repeated injections of gold sodium thiomalate. Agents and Actions, 14, 380–8
Simkin, PA (1976). Oral zinc sulphate in rheumatoid arthritis. Lancet, 2, 539–42
Simkin, PA (1982). Treatment of rheumatoid arthritis with zinc sulphate. In Inflammatory Disease and Copper, ed. Sorenson, JRJ (Clifton, New Jersey: Humana Press), pp. 483–93
Mattingly, PC and Mowat, AG (1982). Zinc sulphate in rheumatoid arthritis. Ann Rheum Dis, 41, 456–7
Rasker, JJ and Kardaun, SH (1982). Lack of beneficial effect of zinc sulphate in rheu matoid arthritis. Scand J Rheumatol, 11, 168–70
Cousins, RJ and Swerdel, MR (1985). Ceruloplasmin and metallothionein induction by zinc and 13-cis-retinoic acid in rats with adjuvant inflammation. Proc Soc Exp Biol Med, 179, 168–72
Withers, AFD, Baker, H, Musa, M and Dormandy, TL (1968). Plasma zinc in psoriasis. Lancet, 2, 278
Greaves, MW and Boyde, TRC (1967). Plasma zinc concentration in patients with psoriasis, other dermatoses and venous leg ulcerations. Lancet, 2, 1019
Voorhees, JJ, Chakrabarti, SE, Botero, E et al. (1969). Zinc therapy and distribution in psoriasis. Arch Dermatol, 100, 669
McMillan, EM and Rowe, D (1983). Plasma zinc in psoriasis: relation to surface area involvement. Br J Dermatol, 108, 301–5
Clemmensen, O J, Siggard-Andersen, J, Worm, AM et al. (1980). Psoriasis treated with oral zinc sulphate. Br J Dermatol, 103, 411–5
Marella, M and Milanino, R (1986). Simple and reproducible method for extraction of copper and zinc from rat tissue for determination by flame atomic absorption spectroscopy. Atomic Spectrosc, 7, 40–2
Rainsford, KD (1982). Environmental metal ion perturbations, especially as they affect copper status, are a factor in the etiology of arthritic conditions: an hypothesis. In Inflammatory Diseases and Copper, (ed.) Sorenson, JRJ (Clifton, New Jersey: Humana Press), pp. 137–43
Oestreicher, P and Cousins, RJ (1985). Copper and zinc absorption in the rat: mechanism of mutual antagonism. J Nutr, 115, 159–66
Brewer, GJ, Hill, GM, Prasad, AS et al. (1983). Oral zinc therapy for Wilson’s disease. Ann Intern Med, 99, 314–20
Hoogenraad, TU, Van den Hamer, CJ and Van Hattum, J (1984). Effective treatment of Wilson’s disease with oral zinc sulphate: two case reports. Br Med J, 289, 273–6
Prasad, AS, Brewer, GJ, Schoomaker, EB and Rabbani, P (1978). Hypocupremia induced by zinc therapy in adults. J Am Med Assoc, 240, 2166–8
Anonymous (1985). Copper deficiency induced by megadoses of zinc. Nutr Rev, 43, 148–9
Patterson, WP, Winkelmann, M and Perry, MC (1985). Zinc-induced copper deficiency: megamineral sideroblastic anemia. Ann Intern Med, 103, 385–6
Festa, MD, Anderson, HL, Dowdy, RP and Ellersieck, MR (1985). Effect of zinc intake on copper excretion and retention in man. Am J Clin Nutr, 41, 285–92
Fischer, PWF, Giroux, A and L’Abbè, MR (1984). Effect of zinc supplementation on copper status in adult man. Am J Clin Nutr, 40, 743–6
Underwood, EJ (1977). Trace Elements in Human and Animal Nutrition, (New York: Academic Press), pp. 56–108
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Kluwer Academic Publishers
About this chapter
Cite this chapter
Frigo, A. et al. (1989). Concerning the potential therapeutic value of zinc in rheumatoid and psoriatic arthritis. In: Milanino, R., Rainsford, K.D., Velo, G.P. (eds) Copper and Zinc in Inflammation. Inflammation and Drug Therapy Series, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2619-6_10
Download citation
DOI: https://doi.org/10.1007/978-94-009-2619-6_10
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7682-1
Online ISBN: 978-94-009-2619-6
eBook Packages: Springer Book Archive