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The Influence of Stressors on the Progression of Neoplastic Change

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Book cover Mechanisms of Carcinogenesis

Part of the book series: Cancer Growth and Progression ((CAGP,volume 2))

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Abstract

It has long been considered that life stressors may have a considerable impact on an individual’s physical well being. To a great extent, this supposition has been based on anecdotal reports that traumatic events or affective changes are frequently associated with illness. Despite its intuitive appeal, experimental data consistent with this position have only recently become available. However, at present, limited information is available concerning the mechanisms subserving the relationship between stressful events and pathology. Evidence from both human and infrahuman research suggests that stressful events may have a profound impact on central neurochemical processes, immune functioning, and the progress of tumor development. The present report will provide a brief review of this literature, with particular emphasis devoted to some of the limiting conditions which influence vulnerability to central neurochemical alterations, immunocompetence and tumor development.

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  1. Hymie Anisman
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  2. Jill Irwin
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  3. Lawrence S. Sklar
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  1. National Cancer Institute, National Institutes of Health, Bethesda, Md., USA

    Elizabeth K. Weisburger

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Anisman, H., Irwin, J., Sklar, L.S. (1989). The Influence of Stressors on the Progression of Neoplastic Change. In: Weisburger, E.K. (eds) Mechanisms of Carcinogenesis. Cancer Growth and Progression, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2526-7_2

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  • DOI: https://doi.org/10.1007/978-94-009-2526-7_2

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7641-8

  • Online ISBN: 978-94-009-2526-7

  • eBook Packages: Springer Book Archive

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