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OH Radicals as Inorganic Bioactivators

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Spectroscopy of Inorganic Bioactivators

Part of the book series: NATO ASI Series ((ASIC,volume 280))

Abstract

The OH free radicals are produced in living organisms as intermediates in normal metabolic processes or during the reactions of catalase, peroxidase and other enzymes1 according to the reactions:

$$O_{2}^{ - } + {{H}_{2}}{{O}_{2}} \to O{{H}^{ - }} + {{O}_{2}} + O{{H}^{\bullet }}$$
((1))
$$F{{e}^{{2 + }}} + {{H}_{2}}{{O}_{2}} \to F{{e}^{{3 + }}} + O{{H}^{ - }} + O{{H}^{\bullet }}$$
((2))

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References

  1. I. Fridovich, in “Advances in Inorganic Biochemistry” ed. by G.L. Eichhorn and L.G. Marzilli, New York, Amsterdam, 1, 67 (1974).

    Google Scholar 

  2. G.E. Adams, in “Advances in Radiation Chemistry”, ed. by M. Burton and J.L. Magee, Wiley-Intercience, New York, London, Vo. 3, pp.125, 1972.

    Google Scholar 

  3. M.N. Schuchmann and C.von Sonntag, J. Chem. Soc. Perkin Trans II, 1958 (1977).

    Google Scholar 

  4. C.von Sonntag, in “The Chemical Basis of Radiation Biology”, ed. by Tayler & Francis, London, New York, Philadelphia, 1988.

    Google Scholar 

  5. J.W.T. Spins and R.T. Woods, “An Introduction to Radiation Chemistry”, ed.Wiley, New York, 1976.

    Google Scholar 

  6. J. Blok, L.H. Luthjens and A.L.M. Roos, Radiat. Res., 30, 468 (1967).

    Article  PubMed  CAS  Google Scholar 

  7. R. Roots and S. Okada, Radiat. Res., 44, 116 (1970).

    Article  Google Scholar 

  8. A.H. Dowdy, L.R. Bennett and S.M. Chastain, Radiology, 55, 879 (1950).

    PubMed  CAS  Google Scholar 

  9. J.D. Anastassopoulou, J.D. Chandrinos and N.Th. Rakintzis, Radiat. Phys. Chem., 17, 55 (1981).

    CAS  Google Scholar 

  10. J.D.Anastassopoulou and N.Th. Rakintzis, Z. phys. Chem. N. F., 141, 53 (1984),

    Article  Google Scholar 

  11. J.D.Anastassopoulou and N.Th. Rakintzis, Z. phys. Chem. N. F., 141, (1984) p.59.

    Article  Google Scholar 

  12. J.D. Anastassopoulou, N.Th. Rakintzis and T. Theophanides, Anticancer Res., 8, 507 (1988),

    PubMed  Google Scholar 

  13. J.D. Anastassopoulou, N.Th. Rakintzis and T. Theophanides, Anticancer Res., 8, 507 (1988) p. 511.

    Google Scholar 

  14. P.T. Emmerson and P. Howard-Flanders, Nature (London), 204, 1005 (1964).

    Article  CAS  Google Scholar 

  15. J.D. Anastassopoulou, Thessis, 1978.

    Google Scholar 

  16. J.D. Anastassopoulou, N.Th. Rakintzis and T. Theophanides, “Spectroscopic Studies and Radiation Effects in Nucleic Acid Components and Their Metal-Adducts”, ed. J.E. Newbery, University of London, Goldsmith’s College, New Cross, London, 1988, in press.

    Google Scholar 

  17. G. Hems, Radiat. Res., 13, 777 (1960).

    Article  PubMed  CAS  Google Scholar 

  18. J.Breculakis, J.Anastassopoulou, N.Th.Rakintzis and T.Theophanides, Chimica Chronica, 1988, in press.

    Google Scholar 

  19. T. Theophanides and J. Anastassopoulou, in “Metal-Based Anti-Tumor Drugs”, ed. M. Gielen, Freund Publishing House Ltd. Tel Aviv, Israel, Vo 1, Chap. 4, p. 151, 1988.

    Google Scholar 

  20. T. Theophanides and J. Anastassopoulou, in “2nd European Conference on the Spectroscopy of Biological Molecules Proceedings”, University of Freiburg, John Wiley & Sons, Eds. E.D. Schmid, F.W. Schneider, F. Siebert, John Wiley & Sons, New York, 1988, p. 433.

    Google Scholar 

  21. P.T. Emmerson, Adv. Radiat. Chem., 3, 209 (1972).

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Radiation Chemistry and Biospectroscopy Laboratory, National Technical University, Zografou Campus, 15 773, Zografou, Athens, Greece

    Jane D. Anastassopoulou

Authors
  1. Jane D. Anastassopoulou
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Editor information

Editors and Affiliations

  1. Department of Chemistry, University of Montreal, Montreal, Quebec, Canada

    Theophile Theophanides

  2. Chemical Engineering Department, National Technical University of Athens, Athens, Greece

    Theophile Theophanides

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© 1989 Kluwer Academic Publishers

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Anastassopoulou, J.D. (1989). OH Radicals as Inorganic Bioactivators. In: Theophanides, T. (eds) Spectroscopy of Inorganic Bioactivators. NATO ASI Series, vol 280. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2409-3_9

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  • DOI: https://doi.org/10.1007/978-94-009-2409-3_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7585-5

  • Online ISBN: 978-94-009-2409-3

  • eBook Packages: Springer Book Archive

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