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Metal Ion-Nucleic Acid Interactions as Studied by Fourier Transform Infrared Spectroscopy

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Spectroscopy of Inorganic Bioactivators

Part of the book series: NATO ASI Series ((ASIC,volume 280))

Abstract

The Fourier Transform Infrared (FT-IR) Spectra of Nucleic Acid molecules and their adducts are summerized and discussed. The potential coordination sites are analyzed in relation to known conformations of the backbone and the bases of DNA. “Marker bands” have been suggested for the conformations, C3’ endo/anti (A-DNA), C2’endo/anti (B-DNA) and C3’endo/syn (Z-DNA). These bands have been observed in FT-IR spectra of metal ion-nucleotide adducts, as well as, in metal ion-DNA adducts, in the regions, 600–900 cm-1 and 1000–1700 cm-1, similar to Raman spectra.

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© 1989 Kluwer Academic Publishers

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Theophanides, T. (1989). Metal Ion-Nucleic Acid Interactions as Studied by Fourier Transform Infrared Spectroscopy. In: Theophanides, T. (eds) Spectroscopy of Inorganic Bioactivators. NATO ASI Series, vol 280. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2409-3_8

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  • DOI: https://doi.org/10.1007/978-94-009-2409-3_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7585-5

  • Online ISBN: 978-94-009-2409-3

  • eBook Packages: Springer Book Archive

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