Abstract
Organometallic reagents, prepared by the reduction of 1,1-dibromoalkanes with TiCl4-Zn, are effective for carbonyl-olefination of esters to give enol ethers regio- and stereoselectively. Reaction with silyl esters and amides gives silyl enolates and enamines, respectively. Organochromium reagents obtained from 1,1-dihaloalkanes and CrCl2 show high chemoselectivity towards aldehydes to give (E)-alkenes.
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© 1989 Kluwer Academic Publishers
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Utimoto, K., Takai, K. (1989). Organometallic Reagents Prepared by the Reduction of Dihaloalkanes with Low Valent Titanium or Chromium. In: Schubert, U. (eds) Advances in Metal Carbene Chemistry. NATO ASI Series, vol 269. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2317-1_41
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DOI: https://doi.org/10.1007/978-94-009-2317-1_41
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