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The role of peptides in the brain

  • Chapter
The Blood-Brain Barrier, Amino Acids and Peptides

Abstract

In the last 10 years there has been an enormous expansion of research on the effect of peptides on the central nervous system. The field has advanced rapidly, which has led to the development of the concept of multiple peptide actions in the central nervous system, under both physiological and pathological conditions. A number of recent experimental and clinical studies have provided strong evidence that the function by which most peptides were originally discovered and characterized is not their usual action, and is often not their most important action. However, from these early studies we have inherited most of the current peptide nomenclature, which in many cases was based on the original proposed function of the peptide.

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Authors and Affiliations

  1. Sherrington School of Physiology, United Medical and Dental Schools of Guys and St Thomas’ Hospital, London, England

    M. B. Segal PhD MPS (Reader in Physiology, Research Associate Professor of Neurosurgery)

  2. Faculty of Medicine, Belgrade, Yugoslavia

    B. V. Zlokovic MD PhD (Associate Professor of Medical Physiology, Research Associate Professor of Neurosurgery)

  3. Childrens Hospital of Los Angeles, University of Southern California, Los Angeles, USA

    M. B. Segal PhD MPS (Reader in Physiology, Research Associate Professor of Neurosurgery) & B. V. Zlokovic MD PhD (Associate Professor of Medical Physiology, Research Associate Professor of Neurosurgery)

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Segal, M.B., Zlokovic, B.V. (1990). The role of peptides in the brain. In: The Blood-Brain Barrier, Amino Acids and Peptides. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2229-7_4

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  • DOI: https://doi.org/10.1007/978-94-009-2229-7_4

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