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Amino acids and the blood-brain barrier

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The Blood-Brain Barrier, Amino Acids and Peptides

Abstract

Amino acids are the structural element of all protein, so their entry from blood into brain is essential for brain growth and metabolism. However, these molecules can have an individual role as powerful neurotransmitters and their level in the brain ISF must be carefully regulated. This homeostasis has several possible sites for control, the entry step from the blood, the uptake and loss from the neurons and glia and the various drainage processes, either by diffusion into the CSF or back across the blood-brain barrier.

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Authors and Affiliations

  1. Sherrington School of Physiology, United Medical and Dental Schools of Guys and St Thomas’ Hospital, London, England

    M. B. Segal PhD MPS (Reader in Physiology, Research Associate Professor of Neurosurgery)

  2. Faculty of Medicine, Belgrade, Yugoslavia

    B. V. Zlokovic MD PhD (Associate Professor of Medical Physiology, Research Associate Professor of Neurosurgery)

  3. Childrens Hospital of Los Angeles, University of Southern California, Los Angeles, USA

    M. B. Segal PhD MPS (Reader in Physiology, Research Associate Professor of Neurosurgery) & B. V. Zlokovic MD PhD (Associate Professor of Medical Physiology, Research Associate Professor of Neurosurgery)

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  1. M. B. Segal PhD MPS
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  2. B. V. Zlokovic MD PhD
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© 1990 Kluwer Academic Publishers

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Segal, M.B., Zlokovic, B.V. (1990). Amino acids and the blood-brain barrier. In: The Blood-Brain Barrier, Amino Acids and Peptides. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2229-7_3

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  • DOI: https://doi.org/10.1007/978-94-009-2229-7_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7500-8

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