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Tuberculosis and Environmental (Atypical) Mycobacterioses: Bacterial Pathological and Immunological Aspects

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Mycobacterial Skin Diseases

Part of the book series: New Clinical Applications: Dermatology ((NCDM,volume 10))

Abstract

For many centuries before the discovery of their causative agents, tuberculosis and leprosy were regarded as being transmissible diseases and in the 19th century tuberculosis of the skin became a well recognized occupational hazard of pathologists, anatomists and butchers1. The transmissible nature of tuberculosis was convincingly demonstrated in an extensive series of experiments on rabbits by Villemin in 1868, and in 1874 Hansen saw the leprosy bacillus in preparations of lesions of patients with lepromatous leprosy. In 1882 Robert Koch isolated the tubercle bacillus in pure culture from various forms of tuberculous lesions, induced the disease experimentally in animals and reisolated the bacilli from lesions in these animals, thereby fulfilling his well-known postulates for the establishment of the aetiology of an infectious disease.

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© 1989 Kluwer Academic Publishers

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Grange, J.M. (1989). Tuberculosis and Environmental (Atypical) Mycobacterioses: Bacterial Pathological and Immunological Aspects. In: Harahap, M. (eds) Mycobacterial Skin Diseases. New Clinical Applications: Dermatology, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2227-3_1

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  • DOI: https://doi.org/10.1007/978-94-009-2227-3_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7499-5

  • Online ISBN: 978-94-009-2227-3

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