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Multinuclear Magnetic Resonance in Liquids and Solids — Chemical Applications pp 81–102Cite as

Two Dimensional NMR Spectroscopy — Basic Principles

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Part of the book series: NATO ASI Series ((ASIC,volume 322))

Abstract

In the past decade there has taken place a steadily increasing expansion of NMR spectroscopy resulting in new applications in chemistry, material sciences, biology, and medicine. The success of this spectroscopic technique to large extent is founded on the introduction of modem one- (1D) and two-dimensional (2D) pulse techniques in Fourier transform NMR spectroscopy1. In the following it is attempted to focus on some basic principles of 2D NMR spectroscopy and to present these ideas within the framework of a simple classical vector model. Therefore this approach mainly aims at preparative chemists who apply NMR spectroscopy for identification and elucidation of structure and dynamics of dissolved compounds. A more detailed and comprehensive treatment of the various aspects of 2D NMR spectroscopy is found in excellent text books1–6 and review articles.7–11

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References

  1. R. R. Ernst, G. Bodenhausen, A. Wokaun, “Principles of Nuclear Magnetic Resonance in One and Two Dimensions”, Clarendon, Oxford, 1987.

    Google Scholar 

  2. A. Bax. “Two-dimensional NMR in Liquids”, Delft University Press, Delft, 1982.

    Google Scholar 

  3. A. E. Derome, “Modern NMR Techniques for Chemistry Research”, Pergamon, Oxford, 1987.

    Google Scholar 

  4. N. Chandrakumar, S. Subramanian, “Modern Techniques in High Resolution FT-NMR”, Springer, New York, 1987.

    Book  Google Scholar 

  5. J. K. M. Sanders, B. K. Hunter, “Modern NMR Spectroscopy”, University Press, Oxford, 1987.

    Google Scholar 

  6. K. Wüthrich, “NMR of Proteins and Nucleic Acids”, Wiley, New York, 1986.

    Google Scholar 

  7. W. P. Aue, E. Bartholdi, R. R. Ernst, J. Chem. Phys., 64 (1976) 2229.

    Article  CAS  Google Scholar 

  8. R. Freeman, G. A. Morris, Bull. Magn. Reson., 1 (1979) 5.

    CAS  Google Scholar 

  9. R. Benn, H. Günther, Angew. Chem., 95 (1983) 381; Angew. Chem. Int. Ed. Engl, 22 (1983) 350.

    Article  CAS  Google Scholar 

  10. G. A. Morris, Mag. Reson. Chem., 24 (1986) 371.

    Article  CAS  Google Scholar 

  11. H. Kessler, M. Gerke, C. Griesinger, Angew. Chem., 100 (1988) 507; Angew. Chem. Int. Ed. Engl., 27 (1988) 490.

    Article  CAS  Google Scholar 

  12. L. Müller, A. Kumar, R. R. Ernst, J. Chem. Phys., 63 (1975) 5490.

    Article  Google Scholar 

  13. G. Bodenhausen, R. Freeman, D. L. Turner, J. Chem. Phys., 65 (1976) 839; R. Freeman, S. P. Kempsell, M. H. Levitt, J. Magn. Reson., 34 (1979) 663.

    Article  CAS  Google Scholar 

  14. G. Bodenhausen, R. Freeman, R. Niedermeyer, D. L. Turner, J. Magn. Reson., 24 (1976) 291.

    CAS  Google Scholar 

  15. J. R. Grabow, D. P. Weitekamp, A. Pines, Chem. Phys. Lett., 93 (1982) 504.

    Article  Google Scholar 

  16. V. Rutar, J. Magn. Reson,. 53 (1984) 87.

    Google Scholar 

  17. R. Benn, “Progress in Terpene Chemistry”, Proc. Conf. Terpene Chem. Grasse (France), Editions Frontieres, Gif sur Yvette, (1986) 317.

    Google Scholar 

  18. K. Nagayama, P. Bachmann, K. Wüthrich, R. R. Ernst, J. Magn. Reson., 31 (1978) 133.

    CAS  Google Scholar 

  19. L. D. Hall, J. K. M. Sanders, J. Am. Chem. Soc., 102 (1980) 5703.

    Article  CAS  Google Scholar 

  20. L. D. Hall, S. Sukumar, J. Am. Chem. Soc., 101 (1979) 3120.

    Article  CAS  Google Scholar 

  21. J. R. Everett, D. W. Hughes, A. D. Bain, R. A. Bell, J. Am. Chem. Soc., 101 (1979) 6776.

    Article  CAS  Google Scholar 

  22. A. A. Maudsley, R. R. Ernst, Chem. Phys. Lett., 50 (1977) 368.

    Article  CAS  Google Scholar 

  23. A. A. Maudsley, L. Muller, R. R. Ernst, J. Magn. Reson., 28 (1977) 463; G. Bodenhausen, R. Freeman, ibid, 28 (1977) 471; R. Freeman, G. A. Morris, J. Chem. Soc. Chem. Commun., 1978) 684.

    CAS  Google Scholar 

  24. G. A. Morris, L. D. Hall, J. Am. Chem. Soc., 103 (1981) 4703.

    Article  CAS  Google Scholar 

  25. D. C. Finster, W. C. Hutton, R. N. Grimes, J. Am. Chem. Soc., 102 (1980) 400.

    Article  CAS  Google Scholar 

  26. H. Kessler, E. Hehlein, R. Schuck, J. Am. Chem. Soc., 104 (1982) 4534.

    Article  CAS  Google Scholar 

  27. T. T. Nakashima, B. K. John, R. E. D. McClung, J. Mag. Reson., 59 (1984) 124.

    CAS  Google Scholar 

  28. P. H. Bolton, G. Bodenhausen, J. Am. Chem. Soc., 101 (1979) 1080.

    Article  CAS  Google Scholar 

  29. H.-J. Gais, J. Vollhardt, H. Günther, D. Moskau, H. J. Lindner, D. Braun, J. Am. Chem. Soc., 110 (1988) 978.

    Article  CAS  Google Scholar 

  30. R. Benn, unpublished results; for the preparation and characterization of these compounds c. f. M. W. Haenel, B. Lintner, R. Benn, A. Rufińska, G. Schroth, C. Krüger, S. Hirsch, H. Irngartinger, D. Schweitzer, Chem. Ber., 118 (1985) 4884.

    Article  Google Scholar 

  31. A. Bax, J. Magn. Reson., 53 (1983) 517.

    CAS  Google Scholar 

  32. H. Kessler, C. Griesinger, J. Zaarbock, H. R. Loosli, J. Magn. Reson., 57 (1984) 331.

    CAS  Google Scholar 

  33. A. Bax, R. Freeman, J. Magn. Reson., 44 (1981) 542.

    CAS  Google Scholar 

  34. K. Nagayama, A. Kumar, K. Wuthrich, R. R. Ernst, J. Magn. Reson., 40 (1980) 321.

    CAS  Google Scholar 

  35. A. Bax, R. Freeman, J. Magn. Reson., 44 (1981) 542.

    CAS  Google Scholar 

  36. M. Rance, G. Wagner, O. W. Sørensen, K. Wuthrich, R. R. Ernst, Biochem. Biophys. Res. Commun., 121 (1984) 1021.

    Article  Google Scholar 

  37. U. Piantini, O. W. Sørensen, R. R. Ernst, J. Am. Chem. Soc., 104 (1982) 6800.

    Article  CAS  Google Scholar 

  38. T. L. Venable, W. C. Hutton, R. N. Grimes, J. Am. Chem. Soc., 104 (1982) 4716; ibid 106 (1984) 7059.

    Google Scholar 

  39. H. Günther, D. Moskau, R. Dujardin, A. Maerker, Tetrahedron Lett., 27 (1986) 2251; D. Barr, W. Clegg, IS. M. Hodgson, R. E. Mulvey, D. Reed, R. Snaith, D. S. Wright, J. Chem. Soc. Chem. Commun. (1988) 367.

    Article  Google Scholar 

  40. G. W. Eich, G. Bodenhausen, R. R. Ernst, J. Am. Chem. Soc., 104 (1982) 3731.

    Article  CAS  Google Scholar 

  41. P. H. Bolton, G. Bodenhausen, Chem. Phys. Lett., 89 (1982) 139.

    Article  CAS  Google Scholar 

  42. A. Bax, R. Freeman, T. A. Frenkiel, M. H. Levitt, J. Magn. Reson., 43 (1981) 478; T. H. Mareci, R. Freeman, J. Magn. Reson., 48 (1982) 158.

    CAS  Google Scholar 

  43. J. Buddrus, H. Bauer, Angew. Chem., 99 (1987) 625; Angew. Chem. Int. Ed. Engl., 26 (1987) 625.

    Article  Google Scholar 

  44. R. Benn, R. Mynott, Angew. Chem., 97 (1985) 330; Angew. Chem. Int. Ed. Engl., 24 (1985) 333.

    Article  CAS  Google Scholar 

  45. C. Brevard, R. Schimpf, G. Tourne, C. M. J. Tourne, J. Am. Chem. Soc., 105 (1983) 7059; R. G. Finke, B. Rapko, R. J. Saxton, P. J. Domaille, J. Am. Chem. Soc., 108 (1986) 2947.

    Article  CAS  Google Scholar 

  46. J. Maxka, B. R. Adams, R. West, J. Am. Chem. Soc., 111 (1989) 3447.

    Article  CAS  Google Scholar 

  47. J. Jeener, B. H. Meier, P. Bachmann, R. R. Ernst, J. Chem. Phys., 71 (1979) 4546.

    Article  CAS  Google Scholar 

  48. G. Bodenhausen, G. Wagner, M. Rance, O. W. Sørensen, K. Wüthrich, R. R. Ernst, J. Magn. Reson., 59 (1984) 542; G. Wagner, G. Bodenhausen, N. Müller, M. Rance, O. W. Sørensen, R. R. Ernst, K. Wüthrich, J. Am. Chem. Soc., 107 (1985) 6440.

    CAS  Google Scholar 

  49. Y. Huang, S. Macura, R. R. Ernst, J. Am. Chem. Soc., 103 (1981) 5327.

    Article  CAS  Google Scholar 

  50. R. Benn, K. Cibura, P. Hofmann, K. Jonas, A. Rufińska, Organometallics, 4 (1985) 2214.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Max-Planck-Institut für Kohlenforschung, Kaiser Wilhelm Platz 1, D-4330, Mülheim a. d. Ruhr, West Germany

    R. Benn

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  1. R. Benn
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Editors and Affiliations

  1. Institut de Chimie, Université Louis Pasteur, Strasbourg, France

    Pierre Granger

  2. Department of Chemistry, Science Laboratories, University of Durham, Durham, UK

    Robin K. Harris

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© 1990 Kluwer Academic Publishers

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Benn, R. (1990). Two Dimensional NMR Spectroscopy — Basic Principles. In: Granger, P., Harris, R.K. (eds) Multinuclear Magnetic Resonance in Liquids and Solids — Chemical Applications. NATO ASI Series, vol 322. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2149-8_7

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  • DOI: https://doi.org/10.1007/978-94-009-2149-8_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7467-4

  • Online ISBN: 978-94-009-2149-8

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