Abstract
Several bacteria have been found to accumulate polyhydroxyalkanoates (PHAs) containing 3-hydroxyvalerate (3HV) and 3-hydroxybutyrate (3HB) monomers from glucose and other carbon sources. These bacteria are members of the taxonomically related genera Rhodococcus, Nocardia and Corynebacterium. The proportion of 3HV and 3HB monomers present in PHA is dependent on the carbon source but 3HV is generally the major 3-hydroxyacid.
Other bacteria, all of which are members of the genus Pseudomonas, accumulate PHA containing 3-hydroxydecanoate (3HD) as the principal monomer from a range of single carbon sources including gluconate and glucose. Since the production of PHAs other than poly-3-hydroxybutyrate (PHB) has hitherto required the use of carbon sources that are related to the required 3-hydroxyacid monomers, bacteria that are capable of producing these PHAs fan single, inexpensive carbon sources are potentially useful for commercial polymer production. The pathways of PHA biosynthesis in both these classes of bacteria clearly differ from those demonstrated, or proposed to occur, in other PHA-synthesizing bacteria.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Dawes, E.A. and Senior, P.J. (1973) Adv. Microb. Physiol. 10, 135–266.
Ballard, D.G.H., Holmes, P.A. and Senior, P.J. (1987) Formation of polymers of ß -hydroxybutyric acid in bacterial cells and a comparison of the morphology of growth with the formation of polyethylene in the solid state. In M. Fontanille and A. Guyot (eds.), Recent advances in mechanistic and synthetic aspects of polymerization, pp. 293–314, D. Reidel Publishing Co., Lancaster, U.K.
Kunioka, M., Nakamura, Y. and Doi, Y. (1988) Polymer Commun. 29, 174–176
Doi, Y., Segawa, A. and Kunioka, M. (1990) Int. J. Biol. Macramol. 12, 106–111.
Doi, Y., Tamaki, A., Kunioka, M. and Soga, K. (1987) Makranol. Chem., Rapid Commun. 8, 631–635.
Lageveen, R.G., Huisman, G.W., Preusting, H., Ketelaar, P., Eggink, G. and Witholt, B. (1988) Appl. Environ. Microbiol. 54, 2924–2932.
Gross, R.A., DeMello, C., Lenz, R.W., Brandl, H. and Fuller, R.C. (1989) Macromolecules 22, 1106–1115.
Bergey’s Manual of Systematic Bacteriology, vol.2 (1987) Ed. P.H.A. Sneath, N.S. Mair, M.E. Sharpe and J.G. Holt, Williams & Wilkins, Baltimore.
Doi, Y., Tamaki, A., Kunioka, M. and Soga, K. (1987) J. Chem. Soc. Commun. 1635–1636.
Brandi, H., Knee, E.J.Jr., Fuller, R.C., Gross, R.A. and Lenz, R.W. (1989) Int. J. Biol. Macranol. 11, 49–55.
Haywood, G.W., Anderson, A.J., Chu, L. and Dawes, E.A. (1988) FEMS Microbiol. Lett. 52, 91–96.
Haywood, G.W., Anderson, A.J., Chu, L. and Dawes, E.A. (1988) FEMS Microbiol. Lett. 52, 259–264.
Haywood, G.W., Anderson, A.J. and Dawes, E.A. (1989) FEHS Microbiol. Lett. 57, 1–6.
Moskowitz, G.J. and Merrick, J.M. (1969) Biochemistry 8, 2748–2755.
Haywood, G.W., Anderson, A.J. and Dawes, E.A. (1989) Biotechnol. Lett. 11, 471–476.
Lessie, T.G. and Phibbs, P.V.Jr. (1984) Ann. Rev. Microbiol. 38, 359–387.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Kluwer Academic Publishers
About this chapter
Cite this chapter
Anderson, A.J., Haywood, G.W., Williams, D.R., Dawes, E.A. (1990). The Production of Polyhydroxyalkanoates from Unrelated Carbon Sources. In: Dawes, E.A. (eds) Novel Biodegradable Microbial Polymers. NATO ASI Series, vol 186. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2129-0_11
Download citation
DOI: https://doi.org/10.1007/978-94-009-2129-0_11
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7458-2
Online ISBN: 978-94-009-2129-0
eBook Packages: Springer Book Archive