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Counterregulation of Stress-Induced Hyperglycemia by Thyrotropin-Releasing Hormone

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Part of the book series: NATO ASI Series ((ASID,volume 54))

Abstract

Hyperglycemia is a frequent metabolic accompaniment of stress, and it is produced by a synergistic stimulatory action of glucagon and catecholamines on glucose production and an inhibitory action of catecholamines on insulin secretion and peripheral glucose utilization. Stress-induced hyperglycemia is most likely adaptive in function for, because the brain receives its energy from circulating glucose, increased metabolic fuel is required during times of stress for normal brain activity. However, if the rise in glucose levels is excessive, deleterious consequences are likely to ensue; glucoregulatory mechanisms most probably also evolved in order to reduce these pathologically elevated sugar concentrations and ensure survival of the organism.

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Amir, S., Pollock, R. (1990). Counterregulation of Stress-Induced Hyperglycemia by Thyrotropin-Releasing Hormone. In: Puglisi-Allegra, S., Oliverio, A. (eds) Psychobiology of Stress. NATO ASI Series, vol 54. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1990-7_12

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  • DOI: https://doi.org/10.1007/978-94-009-1990-7_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7390-5

  • Online ISBN: 978-94-009-1990-7

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