Abstract
After 20 years the question of immunosuppressives in the management of inflammatory bowel disease is no longer a subject for a debate. The scientific evidence is clear and incontrovertible that these drugs are effective in both Crohn’s disease and ulcerative colitis. The lack of acceptance by the medical community is based on: 1) a failure to carefully review uncontrolled and controlled trials; 2) a lack of personal experience in treating patients with these agents; and 3) an unfounded fear of toxicity which has not been observed. The evidence of efficacy from published controlled and uncontrolled trials will be presented with emphasis on the personal series of Dr. Korelitz and myself.
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© 1990 Kluwer Academic Publishers
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Present, D.H. (1990). Immunosuppressive Drugs: Do They Have Any Role in the Treatment of IBD?. In: Rachmilewitz, D., Zimmerman, J. (eds) Inflammatory Bowel Diseases 1990. Developments in Gastroenterology, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1980-8_24
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DOI: https://doi.org/10.1007/978-94-009-1980-8_24
Publisher Name: Springer, Dordrecht
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