Abstract
Highly purified MHC class II positive epithelial cells (EC) from murine small intestine were able to present a soluble antigen (KLH) to a specific class II-restricted CD4 + T cell hybridoma and to induce IL-2 secretion. Antigen presentation in this model was restricted to the H-2 haplotype and could be fully inhibited by anti-la antibodies.
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© 1990 Kluwer Academic Publishers
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Kaiserlian, D., Vidal, K., Blanc, M., Revillard, J.P. (1990). Murine gut epithelial cells present antigen to specific T cell hybridoma. In: MacDonald, T.T., Challacombe, S.J., Bland, P.W., Stokes, C.R., Heatley, R.V., Mowat, A.M. (eds) Advances in Mucosal Immunology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1848-1_6
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DOI: https://doi.org/10.1007/978-94-009-1848-1_6
Publisher Name: Springer, Dordrecht
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